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    As Oncology Nurses, We Are the Fish
    Oncology nurse pride
    As Oncology Nurses, We Are the Fish
    May 20, 2022
    Patients and the Public Recognize and Thank Dedicated Nurses
    Nurse empowerment
    Patients and the Public Recognize and Thank Dedicated Nurses
    May 06, 2022
    How to Promote and Maintain Cancer Screening as COVID-19 Persists
    Cancer screening
    How to Promote and Maintain Cancer Screening as COVID-19 Persists
    March 18, 2022
    I’m a Match: My Journey From Advanced Practice BMT Nurse to Stem Cell Transplant Donor
    Oncology nurse pride
    I’m a Match: My Journey From Advanced Practice BMT Nurse to Stem Cell Transplant Donor
    February 11, 2022
    Online and Mobile Resources Prepare Oncology Professionals for Care Delivery in All Settings
    Oncology nurse pride
    Online and Mobile Resources Prepare Oncology Professionals for Care Delivery in All Settings
    January 31, 2022
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    Research

    Senate HELP Committee Reviews Federal Agencies’ COVID-19 Response
    COVID-19

    Senate HELP Committee Reviews Federal Agencies’ COVID-19 Response

    The Centers for Disease Control and Prevention (CDC) is “committed to continuing to advance the science around COVID-19, moving more vaccines into more communities—especially those communities most at risk for COVID-19 infection—and working to improve health equity,” CDC Director Rochelle Walensky, MD, MPH, said during a March 2021 U.S. Senate Committee on Health, Education, Labor, and Pensions (HELP) hearing. She joined Anthony Fauci, MD, David Kessler, MD, and Peter Marks, MD, PhD, in sharing witness testimonies about their agencies’ response to the pandemic and how to better prepare for future threats.

    July 20, 2021
    FDA Approves Belumosudil for Chronic Graft-Versus-Host Disease
    U.S. Food and Drug Administration (FDA)

    FDA Approves Belumosudil for Chronic Graft-Versus-Host Disease

    On July 16, 2021, the U.S. Food and Drug Administration (FDA) approved belumosudil (RezurockTM), a kinase inhibitor, for the treatment of chronic graft-versus-host disease (chronic GVHD) in adult and pediatric patients 12 years and older after failure of at least two prior lines of systemic therapy. 

    July 19, 2021
    Long-Term irAEs From Checkpoint Inhibitors Have Considerations for Survivorship
    Research

    Long-Term irAEs From Checkpoint Inhibitors Have Considerations for Survivorship

    More than 40% of patients with melanoma treated with nivolumab or pembrolizumab experience persistent long-term immune-related adverse events (irAEs) for at least 1.5 years, researchers reported in JAMA Oncology.

    July 14, 2021
    Nurse Research AIMS to Increase Screening for Malnutrition and Reduce Bowel Dysfunction
    Oncology nurse researcher

    Nurse Researcher AIMS to Increase Screening for Malnutrition and Reduce Bowel Dysfunction

    Research has identified an association between malnutrition and functional deficits in patients with cancer, regardless of age, and other studies confirm that malnutrition affects treatment tolerability, outcomes, and quality of life for patients with cancer. However, studies have also found that oncology clinicians do not consistently assess for malnutrition and functional deficits in clinical settings. 

    July 13, 2021
    The Evidence Is Building for ACE Inhibitors in Anthracycline-Associated Cardiotoxicity
    Research

    The Evidence Is Building for ACE Inhibitors in Anthracycline-Associated Cardiotoxicity

    Cardiac toxicities are associated with many types of cancer therapies, with both length of and time since treatment increasing a patient’s risk for the adverse event. Anthracycline chemotherapies are among the oldest agents still used for a variety of cancer diagnoses, and as cancer survivorship continues to grow, more patients are presenting with late-onset cardiac complications.

    July 13, 2021
    FDA Approves Daratumumab and Hyaluronidase-Fihj With Pomalidomide and Dexamethasone for Multiple Myeloma
    U.S. Food and Drug Administration (FDA)

    FDA Approves Daratumumab and Hyaluronidase-Fihj With Pomalidomide and Dexamethasone for Multiple Myeloma

    On July 9, 2021, the U.S. Food and Drug Administration (FDA) approved daratumumab and hyaluronidase-fihj (Darzalex Faspro®) in combination with pomalidomide and dexamethasone for adult patients with multiple myeloma who have received at least one prior line of therapy, including lenalidomide and a proteasome inhibitor.

    July 12, 2021
    FDA Requires E-Cigarette Brands to Provide Information on Social Media Practices
    U.S. Food and Drug Administration (FDA)

    FDA Requires E-Cigarette Brands to Provide Information on Social Media Practices

    Companies marketing the tobacco brands Aspire, Joyetech, Vaporesso, and Voopoo, which were selected through a systematic process, must share information about social media marketing campaigns that target youth, the U.S. Food and Drug Administration (FDA) announced. The requirements include social media advertising documents and marketing plans, such as planned content to target specific audiences, cost of plans, use of partners and influences, and the number of followers and views broken down by age group.

    July 08, 2021
    USPSTF Recommends Colorectal Cancer Screening Should Begin at 45
    Cancer screening

    USPSTF Recommends Colorectal Cancer Screening Should Begin at 45

    According to the U.S. Preventive Services Task Force (USPSTF), colorectal cancer is the third leading cause of cancer death for both men and women, with an estimated 52,980 individuals in the U.S. projected to die from the disease in 2021. After evaluating the current evidence and conducting a modeling study, USPSTF updated its recommendations on colorectal cancer screening.

    July 05, 2021
    FDA Approves Asparaginase Erwinia Chrysanthemi for Leukemia and Lymphoma
    U.S. Food and Drug Administration (FDA)

    FDA Approves Asparaginase Erwinia Chrysanthemi for Leukemia and Lymphoma

    On June 30, 2021, the U.S. Food and Drug Administration (FDA) approved asparaginase erwinia chrysanthemi (recombinant)-rywn (RylazeTM) as a component of a multiagent chemotherapeutic regimen for the treatment of acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LBL) in adult and pediatric patients one month or older who have developed hypersensitivity to E. coli-derived asparaginase. 

    July 01, 2021
    Immunotherapy Extends Survival in Uveal Melanoma
    Research

    Immunotherapy Extends Survival in Uveal Melanoma

    Patients with uveal melanoma who were treated with tebentafusp, an investigational immunotherapy, lived a median 5.7 months longer than those in comparison groups, researchers reported in study findings presented at the American Association for Cancer Research 2021 annual meeting. 

    June 23, 2021
    FDA Approves Avapritinib for Advanced Systemic Mastocytosis
    U.S. Food and Drug Administration (FDA)

    FDA Approves Avapritinib for Advanced Systemic Mastocytosis

    On June 16, 2021, the U.S. Food and Drug Administration (FDA) approved avapritinib (Ayvakit™) for adult patients with advanced systemic mastocytosis (AdvSM), including patients with aggressive systemic mastocytosis, systemic mastocytosis with an associated hematologic neoplasm, and mast cell leukemia.

    June 17, 2021
    Single-Chain Diabodies May Target Variants in Both Solid and Liquid Tumors
    Cancer research

    Single-Chain Diabodies May Target Variants in Both Solid and Liquid Tumors

    Lab-developed antibodies using a single-chain diabody format can target TP53 or RAS variants in solid tumors and T-cell receptor variants in blood cancers, researchers reported in study findings published in Science, Science Immunology, and Science Translational Medicine, respectively.

    June 16, 2021
    Big Tobacco Continues to Target Female Smokers, but Oncology Nurses Can Help
    Oncology nurse influence

    Big Tobacco Continues to Target Female Smokers, but Oncology Nurses Can Help

    More than 16 million people who identify as women and girls in the United States reported smoking in 2021, according to a May 2021 report from the Campaign for Tobacco Free Kids, of which ONS is an active member, who partnered with several leading women’s organizations on the study. Female smokers are also significantly more likely than men to use menthol cigarettes, and e-cigarette use among high school girls rose by 89% from 2017–2020.

    June 11, 2021
    The Future of Nursing Charts a Path to Achieve Health Equity 
    Health Policy

    The Future of Nursing Charts a Path to Achieve Health Equity 

    Society in 2021 has been challenged by an economic crisis and the COVID-19 coronavirus pandemic. Today, nurses must have an arsenal of tools and knowledge—and the ability to adapt in unpredictable circumstances—to assist patients seeking health care.

    June 11, 2021
    Racial Minorities Receive More Aggressive EOL Ovarian Cancer Care
    Research

    Racial Minorities Receive More Aggressive EOL Ovarian Cancer Care

    During the last month of life, non-White patients are more likely to receive aggressive care with little to no focus on palliative or end-of-life (EOL) care for their ovarian cancer, researchers reported in Cancer.

    June 09, 2021
    Research Findings Confirm Link Between Communication and Safety
    Research

    Research Findings Confirm Link Between Communication and Safety

    My team’s current project to understand communication in ambulatory oncology settings stems from more than a decade of research (Kamimura et al.), in which we have tried to uncover the factors that facilitate high-quality cancer care for patients and a satisfying practice environment for care teams (Friese).

    June 08, 2021
    Multimethod Approach Supports Providers’ Mental Health During COVID-19
    Research

    Multimethod Approach Supports Providers’ Mental Health During COVID-19

    Providing variety of methods and approaches allows healthcare workers to choose the best options for them to mitigate and treat psychological distress from the COVID-19 coronavirus pandemic, researchers said in a preliminary report published in the Joint Commission Journal on Quality and Patient Safety.

    June 02, 2021
    On May 28, 2021, the U.S. Food and Drug Administration (FDA) granted accelerated approval to infigratinib (Truseltiq™), a kinase inhibitor for patients with previously treated, unresectable locally advanced or metastatic cholangiocarcinoma with a fibroblast growth factor receptor 2 (FGFR2) fusion or other rearrangement as detected by an FDA-approved test. FDA also approved the FoundationOne® CDx as a companion diagnostic for infigratinib.
    U.S. Food and Drug Administration (FDA)

    FDA Grants Accelerated Approval to Infigratinib for Metastatic Cholangiocarcinoma

    On May 28, 2021, the U.S. Food and Drug Administration (FDA) granted accelerated approval to infigratinib (Truseltiq™), a kinase inhibitor for patients with previously treated, unresectable locally advanced or metastatic cholangiocarcinoma with a fibroblast growth factor receptor 2 fusion or other rearrangement as detected by an FDA-approved test. FDA also approved the FoundationOne® CDx as a companion diagnostic for infigratinib. 

    June 01, 2021
    Imaging Test Identifies Treatment Choices for ER-Positive Breast Cancer
    Research

    Imaging Test Identifies Treatment Choices for ER-Positive Breast Cancer

    Using positron-emission tomography with a radioactive tracer identifies levels of progesterone receptor in patients with estrogen receptor-positive breast cancer, researchers reported in Nature Communications. The diagnostic tool would help clinicians determine which patients are most likely to respond to hormone therapies for breast cancer.

    May 27, 2021
    Survey Results Support Predicted Effects of Pandemic Screening Drop
    Cancer screening

    Survey Results Support Predicted Effects of Pandemic Screening Drop

    Clinicians are already seeing an increase in late-stage cancer diagnoses that they attribute to the pandemic-driven pause in cancer screening and treatment adherence, according to the results of a survey from the American Society for Radiation Oncology.

    May 26, 2021
    Text Messaging Reduces Disparities in Colorectal Cancer Screening
    Research

    Text Messaging Reduces Disparities in Colorectal Cancer Screening

    A series of text reminders to complete an at-home fecal immunochemical test increased screening completion rates by nearly 20%, researchers reported in study findings published in the Journal of General Internal Medicine. The results are particularly encouraging because almost 90% of the participants were Black, a population that typically has low screening adherence rates but higher incidence of and mortality from colorectal cancer.

    May 19, 2021
    Targeted Therapy Drug Shows Promise in CLL
    Research

    Targeted Therapy Drug Shows Promise in CLL

    Pirtobrutinib, an investigational, third-generation Bruton tyrosine kinase (BTK) inhibitor, offered response rates of 60% or higher in most groups of heavily pretreated patients with chronic lymphocytic leukemia (CLL), even those who’ve received other BTK inhibitors as previous treatment, researchers reported in Lancet.

    May 12, 2021
    Evidence-Based Leadership Trends Show How Every Nurse Is a Leader
    Research

    Evidence-Based Leadership Trends Show How Every Nurse Is a Leader

    I believe that every nurse is a leader, and we need leaders in all areas of our profession, from academia and research to clinical practice. Nurses must lead from the future and reinvent themselves to achieve their desired career path. Practice in the now, but lead from anticipation of what will happen based on healthcare trends.

    May 10, 2021
    Time in Nature Is Time Well Spent
    Nurse well-being

    Time in Nature Is Time Well Spent

    “Nature alone cures,” Florence Nightingale instructed her fellow nurses in Notes on Nursing—and we’ve continued to follow that principle, creating a healing environment for our patients that involves fresh air and sunlight. That same environment can promote health in nurses as well.

    April 29, 2021
    Gut Microbiome May Be a Factor With Immunotherapy Resistance in Advanced Melanoma
    Research

    Gut Microbiome May Be a Factor With Immunotherapy Resistance in Advanced Melanoma

    Altering a patient's gut microbiome through fecal transplant improved response to immune checkpoint inhibitor therapy in 40% of patients with advanced melanoma who initially did not respond to the immunotherapy in a small, single-arm clinical trial. Researchers reported the findings in Science.

    April 28, 2021
    Naproxen Improves Immune Response to Cancer in People With Lynch Syndrome
    Research

    Naproxen Improves Immune Response to Cancer in People With Lynch Syndrome

    The nonsteroidal anti-inflammatory agent naproxen triggers immune cells in the intestinal lining to fight colorectal cancer in people with Lynch syndrome, researchers reported in Gut.

    April 21, 2021
    ONS Members See Beyond Barriers and Understand Benefits of Guidelines
    Research

    ONS Members See Beyond Barriers and Understand Benefits of Guidelines

    I am a clinician in my heart and soul. I was an ONS charter member and one of the first nurse practitioners (NPs) at Memorial Sloan Kettering Cancer Center in New York, NY, before any NP laws were in place and before colony-stimulating factors. The inability to prevent death secondary to chemotherapy-induced neutropenia (CIN) and febrile neutropenia (FN) haunted me and led me to conduct several funded studies. 

    April 19, 2021
    Latina, Asian Women With Gynecologic Cancers Are Less Likely to Use Palliative Care
    Research

    Latina, Asian Women With Gynecologic Cancers Are Less Likely to Use Palliative Care

    Only 4%–9% of patients with ovarian or cervical cancer use palliative care, but the numbers are much lower for Hispanic and Asian women than for non-Hispanic White women, according to researchers’ findings reported in Data in Brief.

    April 14, 2021
    Adding MRI to PSA Detects More Prostate Cancers Than PSA Alone
    Research

    Adding MRI to PSA Detects More Prostate Cancers Than PSA Alone

    Combining magnetic resonance imaging (MRI) with prostate-specific antigen (PSA) testing allows clinicians to detect twice as many clinically significant prostate cancers than PSA testing alone, according to study results published in JAMA Oncology.

    April 07, 2021
    Muscle Quality Predicts Efficacy of NSCLC Immunotherapy
    Research

    Muscle Quality Predicts Efficacy of NSCLC Immunotherapy

    Patients with higher muscle quality during treatment with PD-1/PD-L1 inhibitor monotherapy for non-small cell lung cancer (NSCLC) had higher overall response rates and longer progression-free survival than patients with lower-quality skeletal muscle, researchers reported in study findings published in Cancer Medicine.

    March 31, 2021
    Medicaid Expansion Coincides With Earlier Colon Cancer Diagnosis Rates
    Research

    Medicaid Expansion Coincides With Earlier Colon Cancer Diagnosis Rates

    U.S. states that adopted the Affordable Care Act’s Medicaid expansion in January 2014 have earlier colon cancer diagnoses, enhanced access to care, and improved colon cancer surgical care than states that didn’t implement the expansion, researchers reported in Journal of the American College of Surgeons. Additionally, patients in the expansion states were more likely to have minimally invasive procedures and fewer urgent surgeries.

    February 24, 2021
    COVID-19 Immunity Lasts Multiple Months, NIH Study Shows
    COVID-19

    COVID-19 Immunity Lasts Multiple Months, NIH Study Shows

    Healthcare providers are one of the most at-risk populations for contracting the COVID-19 coronavirus. However, a 2020 study of healthcare workers found that acquired immunity from an initial COVID-19 infection offers protection against reinfection for at least six months or asymptomatic infection in the rare instances where someone subsequently tested positive within six months of acquiring immunity. 

    February 23, 2021
    Mortality Rates After Cancer Surgery Decrease, but Racial Disparities Remain
    Research

    Mortality Rates After Cancer Surgery Decrease, but Racial Disparities Remain

    During the past 10 years, mortality rates after cancer surgery have improved by 0.12%–0.14%, depending on race, researchers reported in study findings published in JAMA Network Open. However, the gap between outcomes for Black and White patients remains, they found.

    February 17, 2021
    Targeted Radiation Reduces Pain From Spine Metastasis
    Research

    Targeted Radiation Reduces Pain From Spine Metastasis

    Palliative radiation targeted directly to the tumor with stereotactic body radiation therapy eliminated metastatic pain in 33% of patients for six months compared to 16% with standard radiation therapy. Researchers reported the study findings at the American Society for Radiation Oncology annual meeting.

    February 10, 2021
    How Can Oncology Nurses Reduce Isolation for Caregivers?
    Research

    How Can Oncology Nurses Reduce Isolation for Caregivers?

    Social connection with others is widely considered a fundamental human need, crucial to well-being and survival. A growing body of literature is evaluating cancer caregivers’ needs, yet strategies to address loneliness, which has broadly detrimental effects on caregivers, are still in their infancy. Therefore, my goal is to identify better support strategies for caregivers as they support their loved ones with cancer.

    February 09, 2021
    Even Short Treatment Delays Affect Cancer Outcomes
    Research

    Even Short Treatment Delays Affect Cancer Outcomes

    Delaying initiation of cancer treatment by just four weeks is associated with increased mortality rates for patients with seven types of cancers, regardless of treatment type, researchers reported in BMJ.

    February 03, 2021
    How Can Innovation and Opportunity Guide a Career in Nursing Research?
    Research

    How Can Innovation and Opportunity Guide a Career in Nursing Research?

    “Nursing is at the forefront of symptom management, and nurse-designed interventions lead the way,” Gwen Wyatt, RN, PhD, FAAN, FAPOS, recipient of the 2020 ONS Distinguished Nurse Researcher Award, said in a session at the inaugural ONS BridgeTM virtual conference in September 2020. She shared lessons from her career journey and told nurses that ONS can help them get their ideas “off the drawing board.”

    January 20, 2021
    Adding Nivolumab to Chemo Improves Survival for Advanced Gastric Cancer
    Chemotherapy

    Adding Nivolumab to Chemo Improves Survival for Advanced Gastric Cancer

    First-line therapy combining nivolumab with chemotherapy improved median overall survival rates in patients with PD-L1-expressing gastric cancer by 3.3 months in a large international, multicenter trial. The findings were reported during the 2020 European Society for Medical Oncology virtual meeting.

    December 30, 2020
    Genomics May Trick PARP Inhibitors to Treat More Cancers
    Research

    Genomics May Trick PARP Inhibitors to Treat More Cancers

    Turning on the body’s inflammasome with epigenetic therapy may improve the efficacy of PARP inhibitors across multiple tumor types, possibly expanding the therapy’s application to new cancers, researchers reported in Proceedings of the National Academy of Sciences.

    December 23, 2020
    Telegenetic Counseling Bridges Geographic Barriers and Minimizes Distress
    Research

    Telegenetic Counseling Bridges Geographic Barriers and Minimizes Distress

    Our 2009–2014 study, Bridging Geographic Barriers: Remote Cancer Genetics Counseling for Rural Women, also known as the REACH Project (Risk Education and Assessment for Cancer Heredity), was the first randomized, noninferiority trial of telephone-based BRCA1 and BRCA2 counseling and testing that used a population-based traceback approach to identify and counsel both rural and urban women who were at increased risk for hereditary breast and ovarian cancer but had not received genetic counseling or testing.

    December 10, 2020
    NKT Cells May Be the Next Wave of CAR Therapy
    Research

    NKT Cells May Be the Next Wave of CAR Therapy

    When genetically modified with a chimeric antigen receptor (CAR), natural killer T (NKT) cells eliminated 50% of metastases in a patient with heavily pretreated, relapsed or refractory metastatic neuroblastoma, according to interim findings from an ongoing study that were published in Nature Medicine.

    December 02, 2020
    FDA Offers Guidance to Enhance Diversity in Clinical Trials
    Cultural/ethnic issues

    FDA Offers Guidance to Enhance Diversity in Clinical Trials

    The COVID-19 coronavirus continues to smother the United States, and nationwide efforts to flatten the curve aren’t lowering cases or preventing deaths. U.S. Food and Drug Administration (FDA) Commissioner Stephen M. Hahn, MD, an oncologist by training and profession, addressed the actions needed to combat COVID-19. One in particular is ensuring that clinical trials accurately reflect diverse populations.

    December 02, 2020
    NIH Turns 80, Shares FDR’s Timeless Message
    Health Policy

    NIH Turns 80, Shares FDR’s Timeless Message

    October 31, 2020, marked an important milestone in American public health: the 80th anniversary of President Franklin Delano Roosevelt’s dedication of the campus of the National Institutes of Health (NIH) in Bethesda, MD. 

    November 30, 2020
    Older Adults Are Being Overscreened for Cancer
    Cancer screening

    Older Adults Are Being Overscreened for Cancer

    Many older adults are continuing cancer screenings beyond the recommended upper age limits, which range from age 65–75 years depending on the type of cancer screening, researchers reported in JAMA Network Open.

    November 25, 2020
    Aspirin’s Cancer Benefits May Not Translate to Older Adults
    Research

    Aspirin’s Cancer Benefits May Not Translate to Older Adults

    Healthy older adults who take daily low-dose aspirin have increased risk of being diagnosed with advanced cancers and dying from cancer, according to findings from a new study published in the Journal of the National Cancer Institute.

    November 18, 2020
    Patients With Gynecologic Cancers Have Significant Fatigue After Surgery
    Cancer surgery

    Patients With Gynecologic Cancers Have Significant Fatigue After Surgery

    Forty-eight percent of women with gynecologic cancers report experiencing clinically significant fatigue after surgery that may continue six months (44%) and one (39%) year later, researchers reported in study findings published in Cancer.

    November 12, 2020
    Research Shows That Telehealth Has the Power to Meet the Needs of Vulnerable Communities
    Research

    Research Shows That Telehealth Has the Power to Meet the Needs of Vulnerable Communities

    Telehealth resources have been present in the United States for several decades. Traditionally, clinicians used telehealth to help rural populations with limited access to care. However, telehealth innovations expand beyond home care coordination. We can use technology to reach even the most remote and vulnerable patients.  

    November 11, 2020
    We Need More Evidence to Assess Technologies for Oral Adherence
    Oral adherence

    We Need More Evidence to Assess Technologies for Oral Adherence

    Oral anticancer agents are often expensive, and ensuring that patients have the financial means to pay for the medication is the first important step to improving adherence rates. Each health system has a group of individuals, not technology, to manage access to financial assistance. Even if they can afford the therapy, however, patients often struggle to maintain oral adherence.

    November 05, 2020
    Nursing Is Science First; It Just Appears Heroic
    ONS Leadership

    Nursing Is Science First; It Just Appears Heroic

    Science, our reliance on the foundations of epidemiology, and management of a public health crisis have been unprecedented discussion topics this year. We have never had a greater need to rely on data, science, and the evolving understanding of experts about the COVID-19 coronavirus and how to contend with it.

    November 02, 2020
    NCI Appoints New Director for Office of Cancer Survivorship
    Survivorship

    NCI Appoints New Director for Office of Cancer Survivorship

    Until recently, past ONS President Deborah Mayer, PhD, RN, AOCN®, FAAN, served as interim director of the National Cancer Institute’s (NCI’s) Office of Cancer Survivorship, a part of the Division of Cancer Control and Population Sciences. As an oncology nurse, Mayer brought a special perspective to the office’s mission to better understand and meet the unique needs of the growing number of U.S. cancer survivors.

    October 29, 2020
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