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    Nursing Students Connect Beyond the Classroom With ONS Resources
    Nursing education
    Nursing Students Connect Beyond the Classroom With ONS Resources
    March 05, 2021
    COVID-19 Affects Cancer Caregivers, but Here Are Ways to Support Them
    COVID-19
    COVID-19 Affects Cancer Caregivers, but Here Are Ways to Support Them
    February 19, 2021
    Celebrate Oncology Nurse Leaders During Black History Month
    ONS Leadership
    Celebrate Oncology Nurse Leaders During Black History Month
    February 03, 2021
    Am I Too Shy to Lead?
    Nurse staffing
    Am I Too Shy to Lead?
    January 29, 2021
    Zoom Through Video Job Interviews With These Tips for Applicants and Hiring Managers
    nursing professional development
    Zoom Through Video Job Interviews With These Tips for Applicants and Hiring Managers
    January 22, 2021
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    Immunotherapy

    ONS Bridge

    Nurses Help Patients Weather the Storm of CAR T-Cell Therapy

    Chimeric antigen receptor (CAR) T-cell therapy is at the forefront of care for a specific subset of patients with cancer. However, the severe side effects of this highly specialized treatment require unique management. During a session for the inaugural ONS Bridge™ virtual conference, Kathleen McDermott, RN, BSN, OCN®, BMTCN®, of Dana-Farber Cancer Institute, discussed how oncology nurses can temper the storm of CAR T-cell therapy.

    September 17, 2020
    ONS Bridge

    Nurses Are Critical to Recognizing Adverse Events From Immune Checkpoint Inhibitors

    Although immune checkpoint inhibitors can be highly effective cancer treatments, potentially even curative in several disease states, they can cause immune-related adverse events in any tissue or organ system, presenters said in a session at the inaugural ONS Bridge™ virtual conference.

    September 15, 2020
    Early Use of Immunotherapy Has Better Outcomes for Bladder Cancer
    Immunotherapy

    Early Use of Immunotherapy Has Better Outcomes for Bladder Cancer

    Starting immunotherapy for bladder cancer shortly after initial treatment with chemotherapy is better than taking an extended break from cancer treatment, according to results from a study reported at the American Society of Clinical Oncology annual meeting.

    August 12, 2020
    Research Is Needed to Better Understand Combination Immunotherapy Side Effects
    Research

    Research Is Needed to Better Understand Combination Immunotherapy Side Effects

    Combination immunotherapy treatments are revolutionizing the way cancer care is delivered. As an ongoing evolution of care, nurses are administering different treatment modalities on a regular basis. Treatments include using multiple immunotherapy drugs in tandem, combining chemotherapy with immunotherapy, using targeted therapies with immunotherapy, and even involving radiation with immunotherapy. The move toward multiple-drug modalities will continue to change nursing practice, and nurses must have a basis of knowledge and evidence from which to work.

    May 12, 2020
    Remodeled CAR T-Cell Therapy May Reduce Side Effects
    Cancer treatments

    Remodeled CAR T-Cell Therapy May Reduce Side Effects

    A new type of remodeled CAR T-cell treatment is just as effective as the original therapy but may result in fewer neurologic side effects, researchers reported in Nature Medicine.

    May 06, 2020
    Harnessing the Abscopal Effect May Change Cancer Care
    Radiation therapy

    Harnessing the Abscopal Effect May Change Cancer Care

    The abscopal effect is a unique phenomenon in cancer treatment that occurs when radiation shrinks untreated tumors found elsewhere in the body in addition to the targeted tumor. The effect has a long history, dating back to the 1950s, but it doesn’t commonly occur in practice and the mechanisms are not fully understood. Research has shown that combining immunotherapy with radiation increases the rate at which the abscopal effect occurs. Understanding how it appears in practice could potentially lead to new cancer treatments and a novel approach to combining immunotherapies with radiation.

    May 05, 2020
    The Next Frontier for Oncology Nursing Care
    Immunotherapy

    Combination Immunotherapy

    Immunotherapies have revolutionized the approach to cancer treatment by leveraging patients’ own immune systems to fight the disease. But the novel therapies have also brought an evolution in traditional treatment regimens through their combination with chemotherapy, radiation, targeted therapy, or even other immunotherapy drugs.

    May 05, 2020
    The Case of the CDK4/6 Inhibitors Checklist
    Immunotherapy

    The Case of the CDK4/6 Inhibitors Checklist

    Three years ago, Sarah, age 54, completed standard chemotherapy and radiation treatment for stage II, ER- and PR-positive, HER2-negative invasive breast cancer. A recent computed tomography scan, ordered to evaluate persistent hip pain, revealed bone lesions, and a biopsy and positron-emission tomography scan confirmed bone-only metastatic breast cancer. A CDK4/6 inhibitor, ribociclib, was added to the letrozole she was already taking.

    February 18, 2020
    CAR T-Cell Therapy Offers Rapid QOL Improvements in Younger Patients
    Patient quality of life

    CAR T-Cell Therapy Offers Rapid QOL Improvements in Younger Patients

    Children and young adults with relapsed or refractory B-cell acute lymphoblastic leukemia reported rapid improvements in quality of life (QOL) after treatment with tisagenlecleucel, a CAR T-cell therapy, according to the results of a study published in Lancet Oncology.

    January 01, 2020
    Do Antibiotics Affect Response to Immune Checkpoint Inhibitors?
    Research

    Do Antibiotics Affect Response to Immune Checkpoint Inhibitors?

    Receiving antibiotics in the 30 days prior to starting immune checkpoint inhibitor treatment was associated with significantly reduced median overall survival, according to findings from a study published in JAMA Oncology. However, antibiotic use during treatment had no effect on survival.

    November 20, 2019
    FDA Grants Accelerated Approval to Zanubrutinib for Mantle Cell Lymphoma
    U.S. Food and Drug Administration (FDA)

    FDA Grants Accelerated Approval to Zanubrutinib for Mantle Cell Lymphoma

    On November 14, 2019, the U.S. Food and Drug Administration (FDA) granted accelerated approval to zanubrutinib (Brukinsa™) for adult patients with mantle cell lymphoma who have received at least one prior therapy.

    November 15, 2019
    Small Study Shows T-Cell Activity in Pancreatic Cancer
    Research

    Small Study Shows T-Cell Activity in Pancreatic Cancer

    When treated with their own nonengineered T cells plus chemotherapy, six of seven patients with inoperable or metastatic pancreatic cancer showed objective responses or stable disease, according to the results of a study reported at the American Association for Cancer Research’s Immune Cell Therapies for Cancer conference in July 2019.

    October 23, 2019
    irAEs Linked to Improved Benefit From Pembrolizumab
    Immunotherapy

    irAEs Linked to Improved Benefit From Pembrolizumab

    Patients with advanced melanoma who received adjuvant therapy with pembrolizumab and subsequently developed immune-related adverse events (irAEs) saw a 63% reduced risk of recurrence, compared to 44% for those who did not develop irAEs. The study findings were presented at the 2019 American Society of Clinical Oncology annual meeting.

    October 09, 2019
    Patient Education Is Critical to Managing irAEs for Immune Checkpoint Inhibitors
    Immunotherapy

    Patient Education Is Critical to Managing irAEs for Immune Checkpoint Inhibitors

    By rebalancing the immune system and re-engaging mechanisms that tumor cells have shut off, immunotherapies such as immune checkpoint inhibitors enable patients’ own bodies to fight their cancers for them. But those same mechanisms can also result in immune-related adverse events (irAEs).

    October 08, 2019
    FDA Rolls Out More New Indications for Existing Agents
    U.S. Food and Drug Administration (FDA)

    FDA Rolls Out More New Indications for Existing Agents

    Pembrolizumab, lenalidomide, and avelumab all received new treatment indications in spring 2019. Here’s what you need to know about dosing, adverse events, and other nursing considerations for these and other drugs that the U.S. Food and Drug Administration (FDA) approved from April–June 2019.

    September 25, 2019
    Pneumonitis With Immunotherapy Treatment
    Immunotherapy

    Pneumonitis With Immunotherapy Treatment

    Pneumonitis is inflammation of the lung parenchyma; although rare, it can be fatal. Nishino et al. found that the overall incidence of pneumonitis with PD-1 inhibitor monotherapy was 2.7% for all-grade and 0.8% for grade 3 or higher pneumonitis. Naidoo et al. reported an approximate 5% incidence of all-grade pneumonitis, although the incidence of all-grade pneumonitis is higher with combination immunotherapy (up to 10%). The incidence is more common with higher grades in PD-1 inhibitors (versus PD-L1 inhibitors), but it occurs less often with anti-CTLA4 monoclonal antibodies. 

    September 23, 2019
    Vaccine May Boost CAR T-Cell Activity in Solid Tumors
    Research

    Vaccine May Boost CAR T-Cell Activity in Solid Tumors

    Researchers are testing a new approach using an amphiphilic cancer vaccine to deliver CAR T-cell therapy to solid tumors, and the results of preclinical studies are promising, according to findings published in the journal Science.

    September 18, 2019
    FDA Approves Combination Pembrolizumab Plus Lenvatinib
    U.S. Food and Drug Administration (FDA)

    FDA Approves Combination Pembrolizumab Plus Lenvatinib

    On September 17, 2019, the U.S. Food and Drug Administration (FDA) granted accelerated approval to the combination of pembrolizumab (Keytruda®) plus lenvatinib (Lenvima®) for the treatment of patients with advanced endometrial carcinoma that is not microsatellite instability high (MSI-H) or mismatch repair deficient (dMMR) and who have disease progression following prior systemic therapy but are not candidates for curative surgery or radiation.

    September 17, 2019
    Melanoma Death Rates Are Falling Fast, Thanks to Immunotherapy
    Immunotherapy

    Melanoma Death Rates Are Falling Fast, Thanks to Immunotherapy

    Two-year survival rates for patients with advanced melanoma increased quickly after the introduction of ipilimumab in 2011, according to an analysis published the journal Cancer.

    September 04, 2019
    Medicare Covers CAR T; HPV Vaccine Confusion; Officials Target Drug Makers
    Health Policy

    Medicare Covers CAR T; HPV Vaccine Confusion; Officials Target Drug Makers

    The decision to allow Medicare to cover the cost of CAR T-cell therapy—a new and expensive form of immunotherapy—is an important one for patients seeking the treatment, especially after rounds of failed tradition therapies. Educating federal agencies and government representatives about the importance of new treatments like CAR T cells have helped drive coverage decisions, and the patient advocacy community—like ONS’s very own advocates—are to thank.

    August 19, 2019
    CMS Makes CAR T-Cell Cancer Therapy Available to Medicare Beneficiaries
    Health Policy

    CMS Makes CAR T-Cell Cancer Therapy Available to Medicare Beneficiaries

    It’s an extraordinary time for biomedical research. Advancements in science, investments in research studies, and an increased access to patients through clinical trials have continued to transform the medical community’s understanding of cancer care and the best ways to treat and cure tumors. Achieving successful outcomes requires specific and dedicated therapies, tailored to each individual.

    August 16, 2019
    CAR T Cells Show Promise in Solid Tumors
    Research

    CAR T Cells Show Promise in Solid Tumors

    Two recent studies demonstrated CAR T-cell therapy activity in certain types of solid tumors, according to results presented at the American Society of Clinical Oncology annual meeting. The CAR T cells used new targets outside of the CD19 targets used for the therapy’s current approvals in leukemia and lymphoma. 
     

    August 14, 2019
    Immunotherapy Experts Identify Key Oncology Nursing Priorities at ONS Summit
    Immunotherapy

    Immunotherapy Experts Identify Key Oncology Nursing Priorities at ONS Summit

    Care coordination, appropriate adverse event assessment and treatment, and rapid, continuous learning are essential priorities for oncology nurses to care for patients receiving immunotherapy, according to the experts who participated in ONS’s immunotherapy summit in March 2018. 

    August 13, 2019
    FDA Approves Pembrolizumab for Advanced Esophageal Squamous Cell Cancer
    U.S. Food and Drug Administration (FDA)

    FDA Approves Pembrolizumab for Advanced Esophageal Squamous Cell Cancer

    On July 30, 2019, the U.S. Food and Drug Administration (FDA) approved pembrolizumab (Keytruda®) for patients with recurrent, locally advanced or metastatic, squamous cell carcinoma of the esophagus (ESCC) whose tumors express PD-L1 (combined positive score [CPS] ≥10), as determined by an FDA-approved test, with disease progression after one or more prior lines of systemic therapy.

    July 31, 2019
    Diagnose and Manage Dermatologic Toxicity Secondary to Immunotherapy
    Advanced practice nursing (APN)

    Diagnose and Manage Dermatologic Toxicity Secondary to Immunotherapy

    Dermatologic toxicity is the most common side effect secondary to immunotherapy. The majority of dermatologic adverse events are mild to moderate rashes on the truck of the body and upper extremities, pruritis, and vitiligo. The most common is maculopapular rash with erythematous macules, papules, and/or plaques that can sometimes be scaly; pruritis is also frequent but often underreported and undertreated and may affect quality of life.

    July 25, 2019
    Oncology Drug Reference Sheet: Atezolizumab’s Indications for Breast and Lung Cancer
    Treatments

    Oncology Drug Reference Sheet: Atezolizumab’s Indications for Breast and Lung Cancer

    The U.S. Food and Drug Administration (FDA) first approved atezolizumab (Tecentriq®) in 2016, but it received additional approvals when used in combination treatments for locally advanced or metastatic triple negative breast cancer (TNBC) and small cell lung cancer (SCLC) in March 2019.

    July 23, 2019
    Fresenius Kabi Issues Voluntary Nationwide Recall of Two Lots of Fluorouracil Injection Because of the Potential for Glass Particulate
    U.S. Food and Drug Administration (FDA)

    Fresenius Kabi Issues Voluntary Nationwide Recall of Two Lots of Fluorouracil Injection Because of the Potential for Glass Particulate

    Fresenius Kabi USA, LLC, is voluntarily recalling two lots of fluorouracil injection, USP 5 g/100 mL (50 mg/mL), 100 mL fill in 100 mL vials, to the user level because of the potential for glass particulate. The affected lots, distributed between December 6, 2018, and February 20, 2019, are listed below:

    July 09, 2019
    Collaboration Is Key to CAR T-Cell Therapy Management Across Settings
    Immunotherapy

    Collaboration Is Key to CAR T-Cell Therapy Management Across Settings

    As of February 2019, only 160 institutions across the United States are certified to administer CAR T-cell therapy, meaning many eligible patients may need to be referred to a treatment center outside of the local ambulatory or community cancer center where they had previously received treatment. The transition from primary oncologist to certified center and back again requires careful coordination to ensure important steps and information aren’t lost.

    July 09, 2019
    FDA Approves Daratumumab for Multiple Myeloma Ineligible for Autologous Stem Cell Transplant
    U.S. Food and Drug Administration (FDA)

    FDA Approves Daratumumab for Multiple Myeloma Ineligible for Autologous Stem Cell Transplant

    On June 27, 2019, the U.S. Food and Drug Administration (FDA) approved daratumumab (Darzalex®) in combination with lenalidomide and dexamethasone for patients with newly diagnosed multiple myeloma who are ineligible for autologous stem cell transplant.

    June 28, 2019
    FDA’s Latest Approved Drugs and Indications Include Two Oral Agents
    U.S. Food and Drug Administration (FDA)

    FDA’s Latest Approved Drugs and Indications Include Two Oral Agents

    Because two oral therapies received new indications in the U.S. Food and Drug Administration’s (FDA’s) most recent round of approvals, oncology nurses will want to focus on ways to manage patients in the home. Assessing oral adherence, encouraging patients to report adverse events, and ensuring their understanding of complex dosing regimens are critical components of nursing care. ONS offers an oral adherence toolkit and oral chemotherapy patient education sheets to help with patient management. 

    June 25, 2019
    FDA Approves Pembrolizumab for Metastatic Small Cell Lung Cancer
    U.S. Food and Drug Administration (FDA)

    FDA Approves Pembrolizumab for Metastatic Small Cell Lung Cancer

    On June 17, 2019, the U.S. Food and Drug Administration (FDA) granted accelerated approval to pembrolizumab (Keytruda®) for patients with metastatic small cell lung cancer with disease progression on or after platinum-based chemotherapy and at least one other prior line of therapy.

    June 17, 2019
    FDA Approves Pembrolizumab for First-Line Treatment of HNSCC
    U.S. Food and Drug Administration (FDA)

    FDA Approves Pembrolizumab for First-Line Treatment of HNSCC

    On June 10, 2019, the U.S. Food and Drug Administration (FDA) approved pembrolizumab (Keytruda®) for the first-line treatment of patients with metastatic or unresectable recurrent head and neck squamous cell carcinoma (HNSCC).

    June 11, 2019
    Survivorship Considerations After CAR T-Cell Therapy
    Immunotherapy

    Survivorship Considerations After CAR T-Cell Therapy

    As more patients receive treatment with chimeric antigen receptor (CAR) T-cell therapy, oncology nurses will need to be aware of the long-term effects of treatment that may persist into survivorship. However, because the treatment is so new, studies measuring those patient-reported concerns are still forthcoming. The majority of today’s recommendations for survivorship management are based on experts’ clinical experience.

    June 11, 2019
    FDA Approves Polatuzumab Vedotin-piiq for Diffuse Large B-Cell Lymphoma
    U.S. Food and Drug Administration (FDA)

    FDA Approves Polatuzumab Vedotin-piiq for Diffuse Large B-Cell Lymphoma

    On June 10, 2019, the U.S. Food and Drug Administration (FDA) granted accelerated approval to polatuzumab vedotin-piiq (PolivyTM), a CD79b-directed antibody-drug conjugate indicated in combination with bendamustine and a rituximab product for adult patients with relapsed or refractory diffuse large B-cell lymphoma, not otherwise specified, after at least two prior therapies.

    June 10, 2019
    Manage Immunotherapy-Related Diarrhea and Colitis
    Advanced practice nursing (APN)

    Manage Immunotherapy-Related Diarrhea and Colitis

    Although immunotherapy has a unique set of toxicities compared to traditional chemotherapy, in general, grade 3 or 4 toxicities are rare—with the exception of grade 3 diarrhea and colitis. The mechanisms by which immune-related diarrhea and colitis occur are not clear. However, T-cell activation leads to high levels of CD4 T-helper cell cytokines and cytolytic CD8 T-cell tissue infiltration. Some research suggests that depleting regulatory T cells also induces autoimmunity.

    June 06, 2019
    Less Toxic CAR T-Cell Therapy May Be on the Horizon
    Treatments

    Less Toxic CAR T-Cell Therapy May Be on the Horizon

    Preliminary results reported in Nature Medicine showed that a redesigned CAR T-cell therapy produced complete response with no severe toxicities in 25 patients with refractory B-cell lymphoma.

    June 05, 2019
    Nurses Are Crucial to Developing Tools, Best Practices for Novel Therapies
    Oncology nurse researcher

    Nurses Are Crucial to Developing Tools, Best Practices for Novel Therapies

    Advanced practice RNs (APRNs), especially those with Doctorate of Nursing Practice degrees, in clinics across the country must not only focus on managing care for patients on novel therapies like immunotherapy but must also look at toxicities and adverse events from a population perspective. APRNs should look across all patients and disease types receiving the same novel treatments and recognize toxicity patterns to determine best practices for patient management. 

    June 04, 2019
    Novel Therapies: How CAR T Cells and Biosimilars Are Changing Cancer Care
    Immunotherapy

    Novel Therapies: How CAR T Cells and Biosimilars Are Changing Cancer Care

    Clinical practice is in a constant state of evolution as new guidelines are released, drugs are approved for new indications, and technology reshapes the way care is delivered. Patients are also arming themselves with a more-advanced-than-ever knowledge and understanding of health care, and providers may be fielding new questions from patients and caregivers about novel treatments such as chimeric antigen receptor (CAR) T-cell therapy and biosimilars. 

    June 04, 2019
    Gut Microbiome Diversity May Improve Response to Melanoma Immunotherapy
    Research

    Gut Microbiome Diversity May Improve Response to Melanoma Immunotherapy

    A high-fiber diet leading to higher gut microbiome diversity may improve response to anti-PD-1 immunotherapy in patients with melanoma, according to the results of a new study presented at the 2019 American Association for Cancer Research Annual Meeting in Atlanta, GA. 

    May 15, 2019
    How APRNs Can Manage Immunotherapy-Related Hypophysitis in Patients With Cancer
    Advanced practice nursing (APN)

    How APRNs Can Manage Immunotherapy-Related Hypophysitis in Patients With Cancer

    Immunotherapy may place patients at risk for distinctive toxicities that differ from traditional chemotherapy. One example is endocrine dysfunction, including hypophysitis, hypo- or hyperthyroidism, type 1 diabetes, and primary adrenal insufficiency. 

    April 25, 2019
    FDA Approves Pembrolizumab Plus Axitinib for Advanced Renal Cell Carcinoma
    U.S. Food and Drug Administration (FDA)

    FDA Approves Pembrolizumab Plus Axitinib for Advanced Renal Cell Carcinoma

    On April 19, 2019, the U.S. Food and Drug Administration (FDA) approved pembrolizumab plus axitinib for the first-line treatment of patients with advanced renal cell carcinoma.

    April 19, 2019
    ONS Congress

    Nurses Must Recognize, Manage Toxicities of CAR T-Cell Therapy

    Chimeric antigen receptor T-cell (CAR T-cell) therapy is an exciting but complex novel form of immunotherapy with multiple potential toxicities that nurses must be prepared to recognize and manage, Misty Lamprecht, MS, APRN-CNS, AOCN®, BMTCN®, of the Ohio State University Comprehensive Cancer Center – James in Columbus said during a session on Saturday, April 13, 2019, at the ONS 44th Annual Congress in Anaheim, CA. Lamprecht’s copresenter was Yi Lin, MD, PhD, of the Mayo Clinic Cancer Center in Rochester, MN.

    April 13, 2019
    ONS Congress

    Combining Radiation With Immunotherapy May Improve Survival

    Combining radiation with immunotherapy can enhance the immune system’s ability to fight cancer, and evidence now suggests that this synergy may lead to improved patient survival, Annette E. Quinn, RN, MSN, of the University of Pittsburgh Hillman Cancer Center, said during a session on Thursday, April 11, 2019, at the ONS 44th Annual Congress in Anaheim, CA.

    April 11, 2019
    ONS Congress

    Resources Are Available to Guide Management of Immunotherapy-Related Adverse Events

    Immunotherapy has evolved into the “fourth pillar” of cancer care, along with surgery, chemotherapy and radiation therapy, according to Laura S. Wood RN, MSN, OCN®, of the Cleveland Clinic Taussig Cancer Center in Ohio and Krista M. Rubin, MS, RN, FNP-BC, of Massachusetts General Hospital in Boston, who spoke during a session on Wednesday, April 10, 2019, at the ONS 44th Annual Congress in Anaheim, CA. Immunotherapeutic agents, however, are vastly different from chemotherapies and have a distinct toxicity profile that advanced practice nurses must be familiar with.

    April 10, 2019
    What Is the Process Called When Natural Killer Cells Target Immunoglobulin G-Coated Cells, Resulting in Cell Lysis?
    Immunotherapy

    What Is the Process Called When Natural Killer Cells Target Immunoglobulin G-Coated Cells, Resulting in Cell Lysis?

    A. Adoptive transfer 

    B. Antibody-dependent cellular cytotoxicity 

    C. Pathogen associated molecular patterns 

    D. Phagocytosis 

    March 22, 2019
    FDA Approves Atezolizumab for Extensive-Stage Small Cell Lung Cancer
    U.S. Food and Drug Administration (FDA)

    FDA Approves Atezolizumab for Extensive-Stage Small Cell Lung Cancer

    On March 18, 2019, the U.S. Food and Drug Administration (FDA) approved atezolizumab in combination with carboplatin and etoposide, for the first-line treatment of adult patients with extensive-stage small cell lung cancer.

    March 19, 2019
    Adding Chemo to Immunotherapy May Resensitize Resistant Tumors
    Immunotherapy

    Adding Chemo to Immunotherapy May Resensitize Resistant Tumors

    Using chemotherapy with immune checkpoint inhibitors may reactivate tumors’ responses to immunotherapy, researchers concluded in a review article published in the Annals of Oncology.

    March 13, 2019
    FDA Approves Atezolizumab for PD-L1 Positive Unresectable Locally Advanced or Metastatic Triple-Negative Breast Cancer
    U.S. Food and Drug Administration (FDA)

    FDA Approves Atezolizumab for PD-L1 Positive Unresectable Locally Advanced or Metastatic Triple-Negative Breast Cancer

    On March 8, 2019, the U.S. Food and Drug Administration (FDA) granted accelerated approval to atezolizumab in combination with paclitaxel protein-bound for adult patients with unresectable locally advanced or metastatic triple-negative breast cancer whose tumors express PD-L1 (PD-L1 stained tumor-infiltrating immune cells [IC] of any intensity covering ≥ 1% of the tumor area), as determined by an FDA-approved test.

    March 11, 2019
    Trump Promises $500 Million Increase to Pediatric Cancer Research
    Cancer health policy

    Trump Promises $500 Million Increase to Pediatric Cancer Research

    Pediatric cancers have more than an 80% overall cure rate, and that, at first glance, seems like something to celebrate. However, in terms of lives lost to different pediatric cancers, the American Cancer Society estimated that more than 1,100 children under the age of 15 will die from their disease in 2019—roughly one in five children diagnosed. Although survival rates are improving in cancers like acute lymphocytic leukemia and Hodgkin lymphoma, other childhood cancer types haven’t seen increased survival since the early 2000s.

    February 26, 2019
    CMS Proposes Medicare Coverage for CAR T-Cell Therapy
    Immunotherapy

    CMS Proposes Medicare Coverage for CAR T-Cell Therapy

    To improve access to new cancer therapies and provide national consistency in coverage, on February 15, 2019, the Centers for Medicare and Medicaid Services (CMS) announced a proposed plan of coverage with evidence development for CAR T-cell therapy. The public is invited to share comments for the next 30 days.

    February 21, 2019
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