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    Clinical and Pharmaceutical Nurse Educators Collaborate to Bring Training to Nurses and Improve Patient Care
    Oncology nurse education
    Clinical and Pharmaceutical Nurse Educators Collaborate to Bring Training to Nurses and Improve Patient Care
    January 13, 2023
    Oncology Nurse Uses Retirement to Help Patients and Healthcare Professionals Understand Pancreatic Cancer Biomarker Testing Results
    Pancreatic cancer
    Oncology Nurse Uses Retirement to Help Patients and Healthcare Professionals Understand Pancreatic Cancer Biomarker Testing Results
    November 11, 2022
    The Life of Marie Curie and Her Contributions to Oncology
    Cancer treatments
    The Life of Marie Curie and Her Contributions to Oncology
    November 07, 2022
    Post-Flooding Natural Disaster Cancer Considerations and Patient Education Points
    Patient safety
    Post-Flooding Natural Disaster Cancer Considerations and Patient Education Points
    September 28, 2022
    Can Patients Use Continuous Glucose Monitors During Radiation Therapy for Cancer?
    Radiation therapy
    Can Patients Use Continuous Glucose Monitors During Radiation Therapy for Cancer?
    August 19, 2022
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    Research

    blood test to detect cancer
    Research

    Blood Test May Detect Tumor-Derived DNA in Early-Stage Cancers

    Researchers have developed a test that detects tiny amounts of cancer-specific DNA in the blood and used it to accurately identify more than half of 138 people with early-stage colorectal, breast, lung, or ovarian cancers. The findings were published in Science Translational Medicine.

    December 06, 2017
    roles of oncology nurses in research
    Research

    NCI Advancements Are Pushing Research Forward for Patients

    Former U.S. Senator Arlen Specter (R-PA) put partisanship aside to support federal funding for biomedical research. And, while battling cancer himself, he spoke about the National Institutes of Health (NIH) and its crucial role in finding treatments and cures. “Health is our nation’s number one asset. Without your health, you can’t do anything. I believe medical research should be pursued with all possible haste to cure the diseases and maladies affecting Americans. I have said many times that the NIH is the crown jewel of the federal government—perhaps the only jewel of the federal government.”

    December 04, 2017
    Using Alternative Medicine Instead of Conventional Cancer Treatments Increases Risk of Death
    Research

    Using Alternative Medicine Instead of Conventional Cancer Treatments Increases Risk of Death

    A large study published in the Journal of the National Cancer Institute found that patients with nonmetastatic breast, lung, or colorectal cancer who chose to use only alternative medicine had substantially worse survival than patients who received conventional cancer treatment.

    November 29, 2017
    Study Finds How Smoking Contributes to Epigenetics of Lung Cancer
    Lung Cancer

    Study Finds How Smoking Contributes to Epigenetics of Lung Cancer

    Although cigarette use has long been linked to lung cancer, scientists have not understood how the earliest changes in lung cells developed. In a study published in Cancer Cell, researchers showed how cigarette smoke sensitized airway cells to genetic mutations that are known to cause lung cancers.

    November 22, 2017
    FDA Update
    U.S. Food and Drug Administration (FDA)

    FDA Approves Sunitinib Malate for Adjuvant Treatment of Renal Cell Carcinoma

    On November 16, 2017, the U.S. Food and Drug Administration (FDA) approved sunitinib malate (Sutent, Pfizer Inc.) for the adjuvant treatment of adult patients at high risk of recurrent renal cell carcinoma following nephrectomy.

    November 17, 2017
    FDA Approves Obinutuzumab for Previously Untreated Follicular Lymphoma
    U.S. Food and Drug Administration (FDA)

    FDA Approves Obinutuzumab for Previously Untreated Follicular Lymphoma

    On November 16, 2017, the U.S. Food and Drug Administration (FDA) granted regular approval to obinutuzumab (Gazyva®, Genentech, Inc.) in combination with chemotherapy, followed by obinutuzumab monotherapy in patients achieving at least a partial remission, for the treatment of adult patients with previously untreated stage II bulky, III, or IV follicular lymphoma (FL).

    November 16, 2017
    FDA Update
    U.S. Food and Drug Administration (FDA)

    FDA Approves Emicizumab-Kxwh for Bleeding in Patients With Hemophilia A With Factor VIII Inhibitors

    On November 16, 2017, the U.S. Food and Drug Administration (FDA) approved emicizumab-kxwh (Hemlibra®, Genentech, Inc.) for routine prophylaxis to prevent or reduce the frequency of bleeding episodes in adult and pediatric patients with hemophilia A (congenital factor VIII deficiency) with factor VIII inhibitors.

    November 16, 2017
    New Imaging Shows Immunotherapy Results in Brain Cancer
    Immunotherapy

    New Imaging Better Shows Immunotherapy Results in Brain Cancer

    Researchers have developed a new approach for brain imaging that can better distinguish immune responses from tumor growth in people with glioblastoma. The findings were published in Proceedings of the National Academy of Sciences.

    November 15, 2017
    Medicinal Mushrooms in Patients With Cancer
    Complementary therapy

    Safety of Medicinal Mushrooms in Patients With Cancer

    Mushrooms have been valued for their health-promoting and medicinal effects for thousands of years. Research over the past few decades has focused on maitake (Grifola frondosa), reishi (Ganoderma lucidum), coriolus (Coriolus versicolor), shiitake (Lentinula edodes), and agaricus (Agaricus blazei), which are predominantly used in Asia.

    November 14, 2017
    FDA Update
    U.S. Food and Drug Administration (FDA)

    FDA Approves Brentuximab Vedotin for Primary Cutaneous Anaplastic Large Cell Lymphoma, CD30-Expressing Mycosis Fungoides

    On November 9, 2017, the U.S. Food and Drug Administration (FDA) granted regular approval to brentuximab vedotin (Adetris®, Seattle Genetics, Inc.) for the treatment of adult patients with primary cutaneous anaplastic large cell lymphoma (pcALCL) or CD30-expressing mycosis fungoides (MF) who have received prior systemic therapy.

    November 09, 2017
    FDA Funds Research Into Health Disparities
    Cancer health disparities

    FDA Funds Research Into Health Disparities

    A wide gap in health disparities continues to exist in the United States, affecting countless underserved and underrepresented Americans. Despite some focus on education, assistance, and outreach, pockets of U.S. citizens are still facing healthcare challenges because of their race, socioeconomic status, location, or other disparities. Because many different factors can contribute to a person’s health, the U.S. Food and Drug Administration (FDA) is dedicating research funding to learn more about how people’s life situations have an impact on their overall health.

    November 09, 2017
    Lancet Oncology Commission Releases Cancer Research Priorities
    Cancer moonshot

    Lancet Oncology Commission Releases Cancer Research Priorities

    The future of oncology care hinges on the implementation of new sciences, the collaboration of researchers, and timeliness with which healthcare professionals can integrate change into practice, according to a new report released by Lancet Oncology.

    November 08, 2017
    Height and Weight May Be Linked to Aggressive Prostate Cancer
    Prostate cancer

    Height and Weight May Be Linked to Aggressive Prostate Cancer

    Taller men and those with a higher body mass index (BMI) may be at increased risk for high-grade prostate cancer and disease-related mortality, according to the results of a study published in BMC Medicine.

    November 02, 2017
    Experimental Three-Drug Treatment May Be Used for Childhood Leukemia
    Leukemia

    Experimental Three-Drug Treatment May Be Used for Childhood Leukemia

    A new treatment approach may eventually help young patients respond better to treatment for acute lymphoblastic leukemia (ALL), according to the results of a new study published in Nature Communications.

    October 25, 2017
    Women Respond Better to Esophageal Cancer Treatment
    Research

    Women Respond Better to Esophageal Cancer Treatment

    Women with locally advanced esophageal cancer that is treated with chemotherapy and radiation therapy before surgery are more likely to have a favorable response to their cancer treatment and less likely to have recurrence than men are, according to the results of a study published in Annals of Thoracic Surgery.

    October 18, 2017
    cancer moonshot initiative impact on oncology nurses
    Cancer moonshot

    What the Next Phase of the National Cancer Moonshot Initiative Means for Oncology Nurses

    In one bold declaration during his final State of the Union Address in 2016, President Barack Obama raised our hopes to a singular goal—ending cancer as we know it—as he announced the National Cancer Moonshot Initiative, now called the Biden Cancer Initiative. Grounded in real research with tangible results, the intent was not even that daring: it was more realistic. Eradicating cancer, now understood to be many different aspects of the same disease, in five years was unlikely, but rather the goal was to achieve in five years what previously would take a decade.

    October 11, 2017
    cancer survivors have higher rate of opioid prescription use
    Research

    Cancer Survivors Have a Higher Rate of Opioid Prescription Use

    Even 10 years after diagnosis and without recurrence, cancer survivors have a higher opioid prescription rate than healthy controls, according to the results of a study published in Cancer.

    October 11, 2017
    Researchers Map More Than 760 Cancer-Dependent Genes
    Research

    Researchers Map More Than 760 Cancer-Dependent Genes

    In an effort to build a comprehensive catalog of genetic causes of cancer, researchers from Harvard and Massachusetts Institute of Technology’s Broad Institute as well as Dana-Farber Cancer Institute have identified more than 760 genes that cells from multiple types of cancer depend on for growth and survival. The findings were published in Cell.

    October 04, 2017
    FDA Update
    U.S. Food and Drug Administration (FDA)

    FDA Grants Accelerated Approval to Nivolumab for HCC

    On September 22, 2017, the U.S. Food and Drug Administration (FDA) granted accelerated approval to nivolumab for the treatment of hepatocellular carcinoma (HCC) in patients who have been previously treated with sorafenib.

    September 25, 2017
    FDA Update
    U.S. Food and Drug Administration (FDA)

    FDA Grants Accelerated Approval to Pembrolizumab for Advanced Gastric Cancer

    On September 22, 2017, the U.S. Food and Drug Administration granted accelerated approval to pembrolizumab (Ketruda®) for patients with recurrent locally advanced or metastatic, gastric or gastroesophageal junction adenocarcinoma whose tumors express PD-L1 as determined by an FDA-approved test. Patients must have had disease progression on or after two or more prior systemic therapies, including fluoropyrimidine- and platinum-containing chemotherapy and, if appropriate, HER2/neu-targeted therapy.

    September 22, 2017
    Dendritic Cell Vaccine
    Immunotherapy

    Dendritic Cell Vaccine Uses Immune System to Fight NSCLC

    A new study testing a dendritic cell vaccine for the first time in humans to treat non-small cell lung cancer (NSCLC) has shown that it successfully amplifies the immune system to boost the effectiveness of anti-PD-1 immunotherapies against the cancer. The findings were published in Clinical Cancer Research.

    September 20, 2017
    cancer research study finds peak time for cancer risk with brca mutations
    Research

    Study Finds Peak Time for Cancer Risk With BRCA Mutations

    Breast cancer risk peaks when a patient is in her 40s for BRCA1 mutations and in her 50s for BRCA2 mutations, according to the results of a new study published in JAMA.

    September 06, 2017
    oncology clinical trial nurses impact cancer care
    Oncology clinical trials

    Oncology Nurses Drive Change In Cancer Care With Clinical Trials

    Clinical trials are responsible for discovering new treatments for cancer as well as the continued evolution of standards of care in clinical practice. Nationally, less than 5% of all eligible adult patients with cancer enroll in clinical trials. Additionally, it takes a drug an average of six to eight years from when it is first introduced in trials to become fully available to all patients who could benefit from it.

    September 05, 2017
    quality improvement, evidence-based practice and research in oncology
    Evidence-based care

    The Difference Between Quality Improvement, Evidence-Based Practice, and Research

    As healthcare institutions become ever more complex and our focus on patient experience expands, nurses are leading and participating in research studies, evidence-based practice (EBP) projects, and quality improvement (QI) initiatives with a goal of improving patient outcomes. Research, EBP, and QI have subtle differences and frequent overlap, which can make it a challenge for nurses to identify the best option to investigating a clinical problem.

    August 29, 2017
    Immunotherapy Communication
    Immunotherapy

    Patient-Provider Communication on Immunotherapy Can Be Improved

    Guidelines regarding healthcare provider communication about immunotherapy do not currently exist. Researchers sought to determine patient and provider preferences for this type of information and to identify barriers to communication about immunotherapy. The study’s findings were presented at the 2017 ASCO Annual Meeting.

    July 19, 2017
    Health Disparities
    Cancer health disparities

    FDA Funds Research Into Health Disparities

    Disparities continue to create a wide gap in health in the United States. Many factors can contribute to a person’s health, and we still have much to learn about the issue. The U.S. Food and Drug Administration (FDA) has announced it will be dedicating research funding to find out more about how lifestyle impacts health.

    May 19, 2017
    Capitol Roundup
    Health Policy

    Nurse Becomes Acting Surgeon General; Representative Roybal-Allard Calls for Funding Scientific Research; Gottlieb Nomination for FDA Commissioner Sent to Senate

    After former President Obama’s surgeon general was asked to resign by the Trump administration, the White House appointed Rear Admiral Sylvia Trent-Adams, PhD, RN, FAAN, as acting surgeon general.

    May 01, 2017
    cancer research finds significant increase in survival rates
    Research

    Annual Cancer Report Identifies Significant Increases in Survival

    As part of its Annual Report to the Nation on the Status of Cancer for 1975-2014, a group of organizations and agencies identified significant increases in cancer survival in the United States, with survival rates more than doubling for eight cancers.

    April 11, 2017
    FDA Announces Oncology Center of Excellence
    U.S. Food and Drug Administration (FDA)

    FDA Announces Oncology Center of Excellence

    The U.S. Food and Drug Administration (FDA) recently announced, through the Office of Health and Constituent Affairs, that it has established the Oncology Center of Excellence (OCE). Longtime FDA official, Richard Pazdur, MD, has been named to lead the division as its first director. The OCE will make oncology “the first disease area to have a coordinated clinical review of drugs, biologics and devices across the agency’s three medical product centers,” according to the FDA.

    March 02, 2017
    Health Policy

    Palliative Care, Opioids, and Biomarkers Lead NIH's 2016 Research Year in Review

    The National Institutes of Health (NIH) has outlined it 2016 research year in review, detailing work done on atomic imaging for drug and protein interactions, biomarkers for prostate cancer, opioid efficacy, and the importance of palliative care. Often lauded as an example of the positive impact that federal agencies can have on Americans, NIH has received welcome support and funding from both sides of the aisle. The research, clinical trials, treatments, and cures that come out of the NIH are life changing and life saving, and all parties in congress recognize its importance.
    January 18, 2017
    Breast cancer

    Mammography Cutoffs Should Be Based on Individual Health History

    Researchers conducting the largest study to date on screening mammography outcomes have found no evidence to support stopping mammography screenings at a certain age. The findings were presented at the 2016 Radiological Society of North America annual meeting.
    January 17, 2017

    Statin Use May Improve Overall Survival From Multiple Myeloma

    A new study has found that use of statin medications in patients with multiple myeloma was associated with a decreased risk of all-cause and cancer-specific mortality. The findings were published in the Journal of Clinical Oncology.
    January 10, 2017
    Access to Cancer Care

    What Is ONS’s Stance on Handling Chemotherapy While Pregnant, Breastfeeding, or Trying to Conceive?

    One of the questions that ONS commonly receives in the clinical inbox (clinical@ons.org) is whether nurses who are pregnant, breastfeeding, or trying to conceive can safely administer or handle chemotherapy and other hazardous drugs.

    January 05, 2017
    Cancer treatments

    Combination Therapy Shows Promise for Chronic Myeloid Leukemia

    According to the results of a new study published in Science Translational Medicine, a combination regimen consisting of a BCR-ABL tyrosine kinase inhibitor and a B-cell lymphoma 2 inhibitor may one day result in a cure for chronic myeloid leukemia.
    January 03, 2017
    Research

    Oncomicrobiotics May Improve Efficacy of Chemotherapy

    The presence of certain intestinal bacteria types may improve the efficacy of alkylating chemotherapy agents such as cyclophosphamide, according to the results of a new study published in Immunity.
    December 20, 2016
    Lung Cancer

    Smoking Causes Higher Proportion of Cancer Deaths in Southern States

    Researchers looked at the burden of cigarette use across all U.S. states and found that the proportion of cancer deaths from smoking was highest in several Southern states, including Arkansas, Kentucky, Louisiana, Tennessee, and West Virginia.
    December 13, 2016
    Research

    CDC Releases Study on Breast Cancer Rates by Age and Ethnicity

    The Centers for Disease Control and Prevention (CDC) released a study in October 2016 that found breast cancer rates among women have decreased in recent years. However, disparities among races and between age groups still exist.
    December 01, 2016
    Oncology nurse researcher

    NINR Sets Strategic Plan for Nursing Research

    On September 15, 2016, the National Institute of Nursing Research (NINR) released its new strategic plan, “Advancing Science, Improving Lives: A Vision for Nursing Science,” citing forward-thinking research.
    October 06, 2016
    Breast cancer

    Neratinib May Be Effective for HER2-Positive Breast Cancer

    According to the results of a phase II, randomized study published in the New England Journal of Medicine, neratinib may effectively treat women with HER2-positive, hormone receptor-negative breast cancer.
    October 04, 2016
    Lung Cancer

    Weight Gain May Indicate Clinical Benefit in NSCLC

    Increasing weight during treatment may indicate early clinical benefit in patients with non-small cell lung cancer (NSCLC), according to the results of a study published in the Annals of Oncology.
    September 27, 2016
    Cancer treatments

    Inotuzumab Ozogamicin May Improve Survival in ALL

    Researchers have found that a monoclonal antibody called inotuzumab ozogamicin may help more patients with refractory B-cell acute lymphoblastic leukemia (ALL) proceed to stem cell transplantation. The findings were reported in the New England Journal of Medicine.
    September 20, 2016
    Cancer screening

    Metastatic Prostate Cancer Increasing in United States

    The number of new U.S. cases of metastatic prostate cancer increased by 72% from 2004–2013, according to a new study published in Prostate Cancer and Prostatic Diseases.
    September 06, 2016
    Oncology drug research

    Maintenance Treatment May Prolong Progression-Free Survival in Ovarian Cancer

    Although response rates to chemotherapy are high, 90% of ovarian cancers will recur within two years. A new drug called niraparib is under investigation as maintenance treatment between cycles of platinum-based chemotherapy, and findings from phase III trials have shown promise.
    August 23, 2016
    Cancer surgery

    Surgery Prolongs Survival for Patients With NSCLC

    Patients with late-stage non-small cell lung cancer who have surgery have better survival rates than those who don’t, according to the results of a recent study published in the Annals of Thoracic Surgery. The researchers also reported that despite the improved survival from surgery, fewer patients are receiving the treatment.
    August 23, 2016
    Cancer treatments

    Poliovirus May Be Key to Treating Glioblastoma

    A phase I study has shown that a small group of patients with recurrent glioblastoma who received treatment with a modified form of poliovirus showed survival improvement over historical controls. The findings, which were not peer reviewed, were presented at the 2016 American Society of Clinical Oncology annual meeting.
    August 16, 2016
    Cancer treatments

    Pembrolizumab Associated With Long-Term Survival in Advanced Melanoma

    A new study has shown that 40% of patients with previously treated advanced melanoma were alive at three years’ follow-up after initiating treatment with pembrolizumab. The results were presented at the 2016 American Society of Clinical Oncology annual meeting.
    August 09, 2016
    Lung Cancer

    Pretreatment Anemia Predicts Poor Survival From NSCLC

    Patients receiving stereotactic body radiation therapy for early-stage non-small cell lung cancer who have anemia at diagnosis may be more likely to have aggressive disease with poor survival and non-local progression, according to findings from a new study published in the Journal of Thoracic Oncology.
    August 02, 2016
    Oncology drug research

    New Class of Drugs Shows Promise in Treatment-Resistant Prostate Cancer

    Researchers in the United Kingdom are looking at a new class of drugs that attacks cancer indirectly through a network of signals, which may prevent or overcome drug resistance. The findings of the study were published in Cancer Research.
    July 26, 2016
    Adverse events

    Sorafenib Adverse Events May Be More Common in Thyroid Cancer

    Researchers have found that patients receiving sorafenib for differential thyroid cancer are more likely to experience adverse events from the drug, compared to patients with renal or hepatocellular cancers. The findings were published in JAMA Oncology.
    July 19, 2016
    Immunotherapy

    What Nurses Need to Know About Talimogene Laherparepvec for Advanced Melanoma

    A number of different oncolytic immunotherapies are in development for advanced melanoma, one of which is talimogene laherparepvec, a genetically modified recombinant herpes simplex virus type 1.
    July 12, 2016
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