November 7, 2022, is the 155th birthday of Maria Sklodowska, who is better known as Madame Marie Curie, one of the greatest minds of chemistry, physics, and radiation oncology. The day also marks the fifth anniversary of #WomenWhoCurie, a social media campaign from the Society for Women in Radiation Oncology that supports and increases visibility of women in radiation oncology.

An eight-week online symptom self-management program, which can be facilitated by a nurse, significantly improves symptom burden, sense of control, and quality of life among patients with ovarian cancer. Researchers reported the evidence in the Journal of Clinical Oncology.

Natural disasters present unique challenges to patients with cancer and the healthcare systems that must stand ready to keep them healthy. Exposure to floodwater places patients at risk for infectious diseases, chemical hazards, and injury, and anything in the water’s path, including medical equipment, medications, homes, and vehicles, can be severely damaged or destroyed. Patients with cancer who are immunocompromised are a highly vulnerable post-flooding population and need special guidance.

Leita, a 42-year-old patient with locally advanced pancreatic cancer, was treated with 5-fluorouracil, irinotecan, and oxaliplatin followed by capecitabine and radiation therapy. After she completed initial treatment, a computed tomography scan conducted in preparation for a possible surgical resection revealed metastatic liver lesions. Leita’s surgery was cancelled, and she began second-line therapy with gemcitabine and nab-paclitaxel.

Survivors need support to resume a high-quality, healthy “new normal” life after they complete their treatment. The services of a cancer survivorship clinic or program may help them manage the physical and emotional implications involved with ongoing care.

To improve cancer care and lower costs, the Centers for Medicare and Medicaid Services created the Enhancing Oncology Model in June 2022.

PITTSBURGH, PA—August 25, 2022—Seven emerging Oncology Nursing Society member leaders under age 40, representing diverse oncology nursing backgrounds around the world, joined the ONS Leadership Development Committee’s 2022 Young Leaders pilot program.

Sally is a 65-year-old patient with T3N1M0 human papillomavirus–negative cancer of the supraglottic larynx who is beginning treatment with radiation and chemotherapy. She has a history of type 1 diabetes mellitus, diabetic retinopathy, diabetic nephropathy, and hospital admissions for diabetic ketoacidosis. She has been using a continuous glucose monitor and insulin pump to help her effectively manage her diabetes. She is concerned that her chemotherapy regimen will involve taking dexamethasone, which will affect her hard-to-control diabetes. Sally tells you she wants to wear her CGM and IP during treatment.

John is a 58-year-old patient who was diagnosed with glioblastoma two years ago. He initially responded well to radiation, temozolomide, and a tumor-treating fields device. His cancer recurred 18 months after diagnosis, and John underwent a second craniotomy that was complicated by a stroke. He became unable to verbally communicate, but John and his partner had previously discussed his desire to participate in clinical trials to help extend his life. The medical oncologist says that John will not qualify for a clinical trial because John is unable to give an informed consent, and John’s partner is frustrated that she can’t speak for him and respect his wishes.

Clinical decision support systems are tools integrated into electronic health records that include reminders for preventive care, evidence-based clinical practice guidelines, order sets, and alerts for drug prescribing. In health care, artificial intelligence converts data into knowledge to guide clinical decisions. When combined, the two technologies can guide advanced practice RNs and other providers with predictions and suggestions that go beyond human accuracy and specificity.

ONS reaps value and benefits from its many collaborations and teamwork—whether between members and staff the Society’s own partnerships with and memberships in other organizations. You may see the outcomes that ONS achieves from those organizational relationships, but you may not yet realize the direct benefit they have for you as well.

Summer is synonymous with vacations, and vacations require logistical preparation. (What will I pack? What should I plan to do?) But it’s also important to ready yourself mentally for a period of wellness and rejuvenation to reap the full benefits of a well-deserved getaway. Making a checklist can help eliminate the stress of both, before and during your travel.

Whole-person care involves evaluating a patient’s physical, emotional, spiritual, and social health. A conversational assessment can help oncology nurses foster an open dialogue about the patient as a person, not just their physical or health needs.

ONS Bridge™, the Oncology Nursing Society’s (ONS’s) premier annual conference tailored to nurses in direct patient care, returns to your screens in September with topics such as care coordination and the latest information on cancer therapies.

Diarrhea is a distressing condition that significantly affects patients’ quality of life and social functioning. Characterized by passage of more than three unformed stools in 24 hours, in cancer it can be caused by chemotherapy, radiotherapy, laxatives and antibiotics, enteral feeding, malabsorption syndromes, colectomy, or several types of malignant tumors. Diarrhea has also been reported in long-term cancer survivors. Standard treatment options such as opiate agonists and adsorbents are associated with side effects that may increase a patient’s symptom burden.

Symptom and pain assessment tools can measure multiple aspects of a patient’s pain experience in both ambulatory and acute care settings. My interest in symptom assessment began with to my work as an oncology nurse practitioner, when I witnessed how symptom management can make a positive difference in patients’ lives and ability to tolerate cancer treatment.

Emerging evidence has consistently shown that flushing central venous catheters with normal saline is comparable to heparin flushes in the adult care setting, leading to updated guideline recommendations that include saline as an alternative. But to date, only two studies have evaluated the two options in pediatric patients, the older of which found increased complications when used in children with leukemia or lymphoma. Is normal saline an acceptable alternative in that population?

Multiple endocrine neoplasia type 1 (MEN1) is a rare autosomal dominant genetic disease affecting about 1 in 30,000 people. Pathogenic variants in the MEN1 gene are associated with benign and malignant tumors in the parathyroid glands, pituitary gland, pancreas, duodenum, and stomach.

Symptom assessment gives oncology nurses a consistent matrix to directly evaluate the significance that symptoms have on patients’ distress, quality of life, and survival. Both symptoms and their impact can evolve throughout a patient’s cancer course, making high-quality and detail-oriented assessments an essential tool for successful treatment and management.

More than a year and a half after a report suggesting a potential racial bias in pulse oximeter technology first surfaced as a letter to the editor in the New England Journal of Medicine (NEJM), on June 21, 2022, the U.S. Food and Drug Administration (FDA) said that it is continuing its investigation into the devices’ accuracy and performance, particularly among people of color.

PITTSBURGH, PA—June 24, 2022—Curated by nurses, for nurses, ONS’s new Biomarker Database connects clinicians to information about therapeutic options for certain cancers and their associated biomarkers. 

Samuel, a 55-year-old patient with a history of T3N1M0 oropharyngeal HPV+ cancer on the base of his tongue, underwent surgery followed by 70 Gy of intensity-modulated radiation over seven weeks with concurrent weekly cisplatin. He responded well and had a positron emission tomography (PET) scan three months post-treatment that showed no cancer. Two months later, Samuel calls the triage line to report swelling on the left side of his neck, the same area where he first noticed a lymph node that led to his initial diagnosis.

Highlighting the most prominent barriers that people accessing care face and the influencers acting on providers, the Centers for Medicare and Medicaid Services (CMS) unveiled in May Chronic Pain Experience Journey Map. The map came out of the work done under the 2019 Chronic Pain Stakeholder Engagement initiative to explore the serious role chronic pain has in patients’ lives.  

Individuals with 10–100+ polyps may have a germline pathogenic variant in the APC gene, placing them at higher risk for developing colorectal, gastrointestinal, and other cancers. The condition is known as familial adenosis polyposis (FAP), and loss of function in the APC gene is the first step in the adenoma-to-carcinoma sequence. Some people have an attenuated form (aFAP), with delayed polyp growth and fewer polyps (see sidebar). As many as 20% are de novo, meaning that they are the first in their family to have an identified pathogenic variant.

Bladder cancer is the sixth most common cancer in the United States, with an estimated 83,730 adult diagnoses in 2021. Smoking is the greatest risk factor (47% of all cases occur in smokers), followed by advancing age and sex (assigned males are four times more likely to develop bladder cancer than those assigned female). The incidence rate in White people is double that of Black people, but Black people are twice as likely to die from the disease.

ONS collaborated with the National Community Oncology Dispensing Association, Hematology/Oncology Pharmacy Association, and Association of Community Cancer Centers to launch the IV Cancer Treatment Education (IVE) online resource. After the success of the highly used Oral Chemotherapy Education (OCE) online resource, the four oncology healthcare organizations expanded their collaboration to launch this new initiative that provides patient and caregiver resources about IV cancer therapies and their side effects.

One of the many lessons we’ve learned since early 2020 is to hope for the best but prepare for the worst. When COVID-19 vaccination rates climbed and infection rates declined in spring 2021, we all confidently looked to September for a return to prepandemic activities. However, the Delta variant’s rapid transmission in July and resulting surge in infection rates paused our plans as the United States reevaluated the safety of a full return without restrictions.

Nursing is among the top careers for job growth, with an estimated 7% increase in the nursing workforce by 2029. As new students train to enter or advance in the profession, advanced practice RNs (APRNs) must mentor and empower them to integrate evidence-based practice (EBP) into their care.

During its June 10–11, 2021, meeting, the ONS Board of Directors held a joint session with the Oncology Nursing Foundation. In small group breakouts, both boards evaluated whether the Foundation’s current academic scholarship opportunities are adequate and responsive to the educational needs of the oncology nursing field. Findings from the sessions were compiled to inform additional discussion during future meetings.

Emerging healthcare technologies require a significant investment in time, money, and training. It starts with ensuring that quality improvement efforts are consistent to support positive clinical and patient outcomes, which is why clinical and information technology (IT) representation is critical in making decisions and exploring solutions. Nursing informatics bridges that gap.

Historically, ovarian cancer is often diagnosed at advanced stages because of vague symptoms and presentation, but with new advancements in diagnosis and treatment options, patients with the disease are living longer than ever.

Malnutrition affects 30%–85% of all patients with cancer, making it one of the most common symptoms for oncology nurses to manage. To help patients achieve the best outcomes, clinicians must understand how and when to screen for malnutrition and how nutritional status affects treatment outcomes and patients’ quality of life.

Nurses are a trusted resource for patient education and offer clarity during a crisis, whether it’s a cancer diagnosis or global pandemic. However, in a survey from the American Nurses Association (ANA), 30% of nurses said they have not received a COVID-19 vaccine, and a quarter of that percentage was still undecided about getting vaccinated. The two main reported reasons were fear of short- and long-term side effects (66%) and lack of information about the vaccines (50%). ANA’s new campaign educates nurses about those concerns.  

Regardless of care setting, oncology nurses must be vigilant about creating a safe environment for and educating patients about the importance of infection prevention. Patients with cancer are at increased risk for viral, bacterial, and fungal infections, but the extent depends on cancer type and treatment. 

Cancer care is always changing, new science is constantly developing, and oncology nurses must work to keep up. ONS’s philosophy is that every nurse has room to develop knowledge, practice, and research. As an organization, we embody a commitment to lifelong learning and professional development because we understand that both are crucial to oncology nursing and patient outcomes.

More than one million nurses and other professionals have received training in end-of-life (EOL) care through the End-of-Life Nursing Education Consortium (ELNEC) program in the past 20 years, the American Association of Colleges of Nursing reported on November 6, 2020. The training has transformed EOL care around the world, including for patients with cancer.

Each year more than 50,000 stem cell transplantations are completed worldwide. The stimulation, harvesting, and therapeutic use of patient and donor cells has evolved as a treatment for diverse cancer diagnoses, and specially trained nurses are at the heart of the clinical trials and care delivery to propel cell transplant therapy across practice settings.

Approximately 700 members responded to ONS’s 2020 genomics survey, which gauged oncology nurses’ current genomic knowledge, applications in practice, and the specific questions they have about genetics and genomics. Here are the answers to the most frequently asked questions based on the survey responses.

The Human Genome Project determined the DNA sequence (order of base pairs) of the entire human genome. Humans are 99.9% identical at the level of base pair ordering, but the 0.1% difference contributes to disease risk. Upon completion of the human genetic blueprint, research turned to identifying and cataloguing genomic variation as well as determining the clinical relevance of variants.

Because of treatment effects on hormones, women with breast cancer and men with prostate cancer have an increased risk of frequent and severe hot flashes after treatment. As many as 80% of patients across both genders experience the symptom, which can have an impact on sleep, mood, energy, and sexual function.

Today’s new normal has changed everything at home, from what we wear to how we teach our children—and in the oncology nursing workplace, from new precautions to the rise of telehealth. It’s also affected nurse residency programs, but one institution has thrived as it adjusted.

Max, a 60-year-old patient with head and neck cancer, is receiving chemoradiation. Since his initial consult, he’s experienced a 12% weight loss from baseline, impaired swallowing, pain, anorexia, and dysgeusia. He has financial challenges, limited social support, poor health literacy, and a history of alcohol abuse. He has a feeding tube, but you suspect he is not using it. You reinforce prior education about malnutrition, and although Max refuses to be admitted to the hospital, he promises to do better.

Half of all healthcare professionals have started using telemedicine in response to the COVID-19 coronavirus pandemic. Patients and providers are trying to adjust to such rapid changes in the provision of health care. Providers want to know how to get reimbursement for telemedicine visits. Society is working together to answer the critical questions about this next wave of health care.

Malfunctioning medical products can pose safety risks to both patients and nurses and waste valuable time and resources. All medical devices and equipment used in the United States must pass specific manufacturing requirements before they can be approved for sale. But every product, regardless of performance, is subject to malfunction. A challenge for nurses is determining whether an issue is a rare failure or if the product is legitimately problematic.

Primary care for patients who are cancer survivors is multifaceted. Although my goal as a primary care physician (PCP) remains the same as with all my patients—to continue helping them lead long, healthy lives—care for this population requires some additional steps. 

With the massive paradigm shift in cancer therapy to precision medicine, the use of biomarkers and biomarker testing has also rapidly evolved to guide treatment selection. However, the terminology used in genomics is complex and inconsistent, and patient advocacy organizations recommend using a common taxonomy to prevent confusion among patients and providers alike. Nurses spend more time with patients and families than any other member of the healthcare team and can reinforce common language and terminology. As a nurse, here are the terms you need to understand.

The COVID-19 coronavirus pandemic forced oncology nurses to navigate abnormal circumstances, both at home and at work. Despite facing similar limitations, the Oncology Nursing Society (ONS) created a brand-new learning experience to give oncology nurses expert education, networking opportunities, and access to industry representatives in the wake of canceled in-person events. This September, ONS will host the inaugural ONS Bridge™, the most comprehensive conference dedicated to oncology nurses.

Doug is a 70-year-old man receiving treatment at the cancer center for metastatic renal cell carcinoma. He was initially treated with sunitinib, a tyrosine kinase inhibitor (TKI). He has been experiencing significant upper back pain and is having trouble with fine motor skills in his fingers. The oncologist, suspecting spinal cord compression (SCC), ordered a computed tomography scan, which confirmed metastatic lesions in the spine leading to instability and mild SCC. The oncologist refers Doug for surgery and advises him that a new medication, cabozantinib, will be ordered for after his surgery. The oncologist asks you, the oncology nurse, to instruct Doug on surgical preparations and educate him on cabozantinib.

It is no coincidence that May is Melanoma Awareness Month. As Americans take to the great outdoors, they also must take caution to protect their skin and prevent melanoma.  

Thrombotic events are the second-leading cause of death in patients with cancer after the disease itself. An estimated 4%–20% of patients experience venous thromboembolism at some stage on the cancer journey.