People aged 50–80 years who are current smokers or have quit and have a smoking history of 20 or more pack-years should be screened annually with low-dose computed tomography, according to the American Cancer Society’s 2023 updated lung cancer screening guidelines.

Veterans younger than age 40 who may have been exposed to burn pits and other toxins during their service are now eligible for breast cancer risk assessments and clinically appropriate mammograms in the Veterans Affairs (VA) health system, the department announced in July 2023.

Compared to standard double reading from two radiologists, artificial intelligence (AI)–supported mammography screening detected one additional breast cancer per 1,000 patients, researchers reported in Lancet Oncology. AI mammography also cut radiologists’ screening workload nearly in half. 

To increase access to and coverage for innovative tests that can detect multiple types of cancer, U.S. Senators Mike Crapo (R-ID), Michael Bennet (D-CO), Tim Scott (R-SC), and Ben Cardin (D-MD) reintroduced the Medicare Multicancer Early Detection Screening Coverage Act. Bipartisan companion legislation was also introduced in the U.S. House of Representatives.  

Currently under study, multicancer early detection (MCED) tests have the potential to fill gaps in the screening process for some cancers, consequently leading to earlier diagnoses for cancers historically diagnosed at later stages because of a lack of screening options. MCED tests use various methods to detect multiple cancers from one blood sample, such as methylation-based assay, which analyzes methylation patterns in cell-free DNA. In cancer cells, hypermethylation may silence tumor suppressor genes in the early stages of cancer growth. DNA hypermethylation has become a promising biomarker for early cancer detection. 

Remote educational outreach involving oncology nurse–developed videos and follow-up navigator phone calls increased breast, cervical, and colorectal cancer screening adherence compared to usual care in females obtaining community care in rural Ohio and Indiana locations, according to study findings published in JAMA Network Open.

After remaining largely stable from 2011–2019, cancer incidence rates dropped sharply in 2020 while mortality remained level, the Centers for Disease Control and Prevention said in its 2023 U.S. Cancer Statistics report.

First responders’ persistent exposures to toxic chemicals, abnormal sleep schedules, and constant stress may lead to a higher risk of developing cancer. In particular, firefighters have a 9% higher risk for a cancer diagnosis and a 14% higher risk of cancer mortality compared to the general population.

Race, sex, education level, and healthcare coverage status all contribute to cancer screening disparities among sexual and gender minority populations, researchers reported in the March 2023 issue of the Oncology Nursing Forum.

Because of insufficient evidence, the U.S. Preventive Services Task Force’s (USPSTF’s) 2023 skin cancer recommendations advise that “the balance of benefits and harms for visual skin examination by a clinician to screen for skin cancer in asymptomatic adolescents and adults cannot be determined.” For breast cancer, the USPSTF’s 2023 recommendation stated that all women should get screened every other year, starting at age 40.

U.S. healthcare providers need improved access to interventions known to prevent common causes of cancer death so the country can achieve President Joe Biden’s Cancer Moonshot initiative goal of reducing the cancer death rate by at least 50% over the next 25 years, according to a National Institutes of health study published in April 2023 that was led by National Cancer Institute researchers.

For nearly 2,500 years, nonmaleficence, or “do no harm,” has been a fundamental tenet of medical ethics. Yet none of today’s U.S. breast, cervical, colorectal, lung, or prostate cancer screening guidelines report all of the harms associated with screening tests, researchers said in study results published in Annals of Internal Medicine.

Patient navigation services must increase breast, cervical, and colorectal cancer screening for disadvantaged racial and ethnic populations and people with lower incomes, the Community Preventive Services Task Force recommended. Patient navigation services, coupled with timely and appropriate follow-up care and treatment, could improve health equity for these groups, in some cases reducing cancer mortality and incidence, the task force added. 

Increases in early-stage lung cancer diagnoses with low-dose computed tomography screening have led to sustained improvements in survival rates more than 20 years later, researchers said while presenting their study findings at the 2022 Radiological Society of North America annual meeting.

The U.S. Food and Drug Administration updated its mammography regulations in March 2023 to require institutions to notify patients about their breast density. The updated regulations strengthen FDA’s oversight and enforcement of institutions and help healthcare providers better categorize and assess mammograms.

Most patients at high risk for developing pancreatic cancer whose disease was found while participating in a screening program were diagnosed with early-stage cancers, according to study findings published in the Journal of Clinical Oncology.

The U.S. Department of Health and Human Services, through the Health Resources and Services Administration, awarded more than $5 million in September 2022 to 11 HRSA-funded community health centers to help underserved populations access cancer screenings and early detection services in partnership with National Cancer Institute-designated cancer centers.

Monitoring early-stage testicular cancer survivors for disease recurrence after surgery using either magnetic resonance imaging or fewer computed tomography scans is just as effective as more frequent intervals, researchers reported in study findings published in the Journal of Clinical Oncology.

To support the objectives of President Joe Biden’s relaunched Cancer Moonshot initiative, the Centers for Disease Control and Prevention awarded $215 million to three national cancer programs in June 2022. The funds are part of a $1.1 billion investment in cancer prevention and control.

Although regular population-based skin cancer screening isn’t recommended by the U.S. Preventive Services Task Force, more Americans are getting full-body skin exams at dermatology visits or other provider services. Data from a new study published in JAMA Dermatology suggest that the screening uptick is associated with increased diagnoses of early-stage, in situ melanoma, leading the researchers to raise concerns about overdiagnosis.

With the relaunch of the Biden-Harris administration’s Cancer Moonshot initiative, the fight against cancer is back in the government spotlight. To support the Moonshot’s goals, in May 2022 the U.S. Department of Health and Human Services (HHS) allocated $5 million to the Health Resources and Services Administration-funded community health centers.

Patients who take anxiety or depression medication are more likely to obtain prostate-specific antigen tests, according to study findings that researchers presented at the 2022 American Society of Clinical Oncology Genitourinary Cancers Symposium.

Nearly a quarter of patients who are eligible for cervical cancer screening are overdue for their current tests, researchers said in study findings published in JAMA Network Open. The number grew nearly 10% since 2005—representing a steady increase in missed screening over time—and was higher in different sociodemographic groups because of factors related to social determinants of health.

“Cancer doesn’t wait, and neither should you,” the Centers for Disease Control and Prevention (CDC) urged patients in its new cancer screening adherence campaign. The COVID-19 pandemic has created barriers to regular health visits, screenings, and treatment for individuals everywhere, and providers and organizations alike are seeking solutions.

Responses to pandemic-related screening and treatment delays have created new opportunities for oncology advanced practice RNs (APRNs), too. In both their institutions and communities, APRNs are guiding patients and providers to reverse the increases in late cancer diagnoses, morbidity, and mortality—ultimately improving outcomes.

More Medicare beneficiaries now meet age, smoking history, and other criteria for lung cancer screening and are now eligible to receive low-dose computed tomography (LDCT), according to a February 2022 memo from the Centers for Medicare and Medicaid Services (CMS).

For the past two years, patients and providers have turned their attention to combatting a global health threat. We’ve nearly crumbled amid the chaos, but carried on through acts of comfort and innovation. However, as we pled for an end to this nightmare, for heard immunity through vaccination, another health threat took a backseat. Cancer screening rates plummeted, particularly among communities of color. Oncology nurses can use evidence-based interventions to increase screening rates for all patients with cancer.  

Comprehensive preventive care and screening guidelines for women and infants, children, and adolescents under the Affordable Care Act expanded in January 2022, requiring certain group health plans and insurance plans to provide coverage with no out-of-pocket costs for preventive health services, according to the U.S. Department of Health and Human Services (HHS) and U.S. Health Resources and Services Administration (HRSA).

Compared to people living in urban areas, on a nationwide U.S. survey, rural populations were more likely to report believing that cancer is unpreventable and always fatal. Researchers reported the survey findings and analysis in Cancer Epidemiology, Biomarkers, and Prevention.

Multimedia tools and resources can help patients learn more about a cancer diagnosis, treatment regimens, procedures, and follow-up care, among other important topics, and many institutions and organizations have jumped onto the bandwagon to create those resources for their patients. A new video series on gynecologic cancers from the Centers for Disease Control and Prevention (CDC) adds another patient education resource to oncology nurses’ toolbox.

All cells (healthy cells and tumor cells) in the body shed DNA, called cell-free DNA (cfDNA). When it’s only from tumor cells, it’s referred to as circulating tumor DNA (ctDNA), although cfDNA and ctDNA are sometimes used interchangeably.

Colorectal cancer (CRC) screening may be beneficial for certain patients aged 75–85, according to findings from a new study. The researchers reported the results in JAMA Oncology.

African Americans have a higher cancer burden and face greater obstacles to cancer prevention, detection, treatment, and survival, according to the American Cancer Society. Health organizations such as ONS and the U.S. Food and Drug Administration (FDA) are dedicated to breaking down barriers and improve access to quality care and resources for those patients. To increase cancer awareness in one of the most vulnerable segments of the U.S. population, the FDA’s Oncology Center of Excellence (OCE) dedicated June 17–23, 2021, as National Black Family Cancer Awareness Week.

According to the U.S. Preventive Services Task Force (USPSTF), colorectal cancer is the third leading cause of cancer death for both men and women, with an estimated 52,980 individuals in the U.S. projected to die from the disease in 2021. After evaluating the current evidence and conducting a modeling study, USPSTF updated its recommendations on colorectal cancer screening.

Clinicians are already seeing an increase in late-stage cancer diagnoses that they attribute to the pandemic-driven pause in cancer screening and treatment adherence, according to the results of a survey from the American Society for Radiation Oncology.

A series of text reminders to complete an at-home fecal immunochemical test increased screening completion rates by nearly 20%, researchers reported in study findings published in the Journal of General Internal Medicine. The results are particularly encouraging because almost 90% of the participants were Black, a population that typically has low screening adherence rates but higher incidence of and mortality from colorectal cancer.

Cancer mortality rates decreased by 27% from 1999–2019, the Centers for Disease Control and Prevention (CDC) reported in February 2021. However, cancer remains the one of the leading causes of death in the United States, second only to heart disease, and disparities remain. More needs to be done to decrease risk and increase prevention.

Sally, a nurse practitioner in a cancer survivorship clinic, is preparing to discuss screening and surveillance guidelines with Jonah, a 32-year-old survivor of Hodgkin lymphoma. Sally reviews Jonah’s patient history form and notes that Jonah uses he and him pronouns. His gender identity is male and sex assigned at birth was female. Jonah’s surgical history includes gender-affirming surgery on chest tissue (also known as top surgery), and his current medications include supplemental testosterone. Jonah also specifies that he is transmasculine—an umbrella term used to indicate that Jonah feels a connection with masculinity.

Reduced adherence to recommended screening and prevention relates to a lack of knowledge and barriers like inadequate insurance, low engagement with primary care, time constraints, and misconceptions about risks of screening or their individual risk of developing cancer. We must do a better job of educating people about cancer screening and linking them to affordable or free services. 

To increase access to breast and cervical cancer screening, U.S. Congress passed the Breast and Cervical Cancer Mortality Prevention Act of 1990, which led to the creation of the National Breast and Cervical Cancer Early Detection Program (NBCCEDP). Because of NBCCEDP, eligible women who are low-income, underserved, and underinsured receive free breast and cervical cancer screening and diagnostic testing. 

The draft 2020 U.S. Preventive Services Task Force (USPSTF) lung cancer screening recommendations were intended to increase the number of high-risk minorities eligible for lifesaving tests. And they do, but not as much as USPSTF anticipated, still leaving gaps and disparities, researchers reported in the Journal of the National Cancer Institute. They created a risk model to augment the guidelines that eliminated the disparities for most racial groups.

Nearly 1.9 million people in the United States will be diagnosed with cancer in 2021. However, overall cancer screenings dropped roughly 80% in 2020 because of the COVID-19 coronavirus pandemic and statewide stay-at-home orders. To combat the decline, the Centers for Disease Control and Prevention’s (CDC’s) new outreach campaign reminds patients and providers of the importance of cancer screening. 

Patient education is an essential aspect of cancer prevention. Nearly 1.9 million people in the United States will be diagnosed with cancer in 2021, and modifiable risk factors are responsible for approximately 35% of cancer-related deaths. However, less than half of Americans understand the major risk factors that contribute to the development of cancer.

U.S. states that adopted the Affordable Care Act’s Medicaid expansion in January 2014 have earlier colon cancer diagnoses, enhanced access to care, and improved colon cancer surgical care than states that didn’t implement the expansion, researchers reported in Journal of the American College of Surgeons. Additionally, patients in the expansion states were more likely to have minimally invasive procedures and fewer urgent surgeries.

Many older adults are continuing cancer screenings beyond the recommended upper age limits, which range from age 65–75 years depending on the type of cancer screening, researchers reported in JAMA Network Open.

Lung cancer is the leading cause of cancer death in the United States, accounting for about one quarter of cancer deaths, and more than a quarter of million lung cancer diagnoses are projected in the United States for 2020. Lung cancer has various types, pathologies, and histologies, each with its own prognosis and treatment plan. Non-small cell lung cancer consists of about 80%–85% of lung cancer diagnoses.

People with a cervix who are aged 25–65 years should receive a human papillomavirus (HPV) test every five years, according to the new American Cancer Society (ACS) guidelines for cervical cancer screening.

The urinary system, including the bladder, ureters, urethra, and renal pelvis, is lined with urothelial tissue. Urothelial carcinoma is the predominant histologic type of cancer in that system, and 90% of tumors are located in the bladder. With more than 81,400 new cases and nearly 18,000 deaths estimated for 2020, bladder cancer is the fifth most prevalent type of cancer in the United States.

Patients who watch crime shows think that DNA testing is as simple as taking a cheek swab and getting the results in two minutes so the case is solved at the end of the 42-minute episode. The reality? DNA can be identified from buccal cells in a cheek swab, but results take several weeks to obtain and are not always a simple negative or positive.

When combined with positron-emission and computed tomography, a multicancer blood test identified 10 different tumor types in a sample of women with no history of cancer, researchers reported in Science.