Genetic Disorder Reference Sheet: BAP1
Isolated in 1998 as a tumor suppressor gene, BAP1 pathogenic variants have been identified in at least 200 families. More cases will be found as germline pathogenic variant testing becomes more readily available and routinely offered to patients with cancer.
Religious Fasting During Cancer Treatment
Many cultures and religions across the world practice fasting, or the absence of caloric intake for a few hours to several weeks, at different times throughout the year. Islam, Judaism, Buddhism, Christianity, Hinduism, and Taoism religions most commonly use fasting for various reasons, but the overall purpose generally is to demonstrate sacrifice or spiritual cleansing.
Clinical and Pharmaceutical Nurse Educators Collaborate to Bring Training to Nurses and Improve Patient Care
In 2022 we celebrated the National League for Nursing’s Year of the Nurse Educator, but nursing staff recognize and thank nurse educators for their critical role in training and support year in and year out. Oncology nurses in particular rely on nurse educators to stay updated as treatments and patient care constantly evolve—and that requires a multipronged approach. All aspects are covered when clinical nurse educators and pharmaceutical nurse educators come together to deliver training for today’s cancer therapies.
Text-Messaging Prescreening Streamlines Treatment Visits and Care for ICI Toxicities
Prescreening patients for immune-related adverse events during treatment with immune checkpoint inhibitors using text messaging may reduce the need for some in-person, preinfusion office visits, researchers reported in JAMA Network Open. The approach may help decrease the burden of cancer care for both patients and providers.
Micro-Organospheres Create Molecular Model of Patients’ Cancer in Just Two Weeks
Biomarker- and molecular-driven technologies such as molecular models can precisely predict how an individual’s cancer will respond to certain treatments, the pinnacle of precision oncology. However, established modeling systems such as patient-derived xenografts and patient-derived organoids require large tissue samples and take months or even a year to obtain results, barriers that have limited their application in regular practice.
Predictive and Diagnostic Biomarkers
Biomarkers, also called molecular markers or signature molecules, can help clinicians characterize alterations in tumors through the detection of specific DNA, RNA, protein, or metabolomic profiles. These pieces of the cancer puzzle are part of precision oncology that the cancer care team can use to assess patients’ cancer risk and prognosis or monitor disease progression. Biomarkers are also a key factor in determining and tailoring treatment methods and their likelihood of success.
NCI Awards $23 Million to Establish Centers to Study Telehealth for Cancer Care
Four academic institutions will create centers of excellence dedicated to telehealth in cancer care to help healthcare providers increase its use in oncology practice, thanks to $23 million in National Cancer Institute (NCI) funding. The awards are part of NCI’s Telehealth Research Centers of Excellence initiative, which is supported by President Joe Biden’s Cancer Moonshot initiative.
Most Lung Cancer Genetic Variants Are Clinically Actionable and All Patients Should Get Biomarker Testing
More than 95% of germline genetic variants identified through genetic testing in patients with lung cancer are potentially clinically actionable, researchers reported in study findings during the 2022 ASCO Plenary Series Program, leading them to recommend testing all patients with the disease.
Genetic Counselors Help Patients and Oncology Nurses Predict Current and Future Cancer Diagnoses
Many of our patients are individuals who haven’t developed cancer but might have a concerning family history of the disease. We rely on healthcare providers like oncology nurses to identify individuals with concerning cancer histories and refer them to genetic counselors for a complete risk assessment, including genetic testing when appropriate, to determine their risk and recommend proactive measures to reduce it.
CHIP Drastically Reduced Uninsured Children in the Past 25 Years
The Children’s Health Insurance Program helped drop the percentage of uninsured children from 15% to 3.7% since its authorization by Congress in 1997, according to data from the U.S. Department of Health and Human Services and the Centers for Medicare and Medicaid Services released in celebration of CHIP’s 25th anniversary in August 2022.
New SIO-ASCO Guideline Identifies Integrative Care Recommendations for Cancer-Related Pain
Cancer-related pain, whether from the disease or its treatments, is a distressing symptom that persists through survivorship. Pain diminishes patients’ quality of life and negatively affects their cancer-related outcomes.
Sexual Considerations for Patients With Cancer
As a term, sexuality is linked to sexual functioning—the ability to engage in sexual behaviors and the body’s physiologic response—as well as sexual reproduction and fertility. But those biologic aspects are just a small part of a person’s overall sexuality. Sexual health is a state of physical, emotional, mental, and social well-being and requires a positive and respectful approach to sexuality and sexual relationships.
CMS Guides U.S. States on New Benefit to Improve Access to Care for Children With Complex Medical Conditions
A new Medicaid health home benefit could improve access to person-centered care management, care coordination, and support resources for children with complex medical conditions and their families—but only if states understand how to opt into offering it. In August 2022, the U.S. Department of Health and Human Services, through the Centers for Medicare and Medicaid Services, released guidelines for states to better understand the benefit and its requirements.
Post-Flooding Natural Disaster Cancer Considerations and Patient Education Points
Natural disasters present unique challenges to patients with cancer and the healthcare systems that must stand ready to keep them healthy. Exposure to floodwater places patients at risk for infectious diseases, chemical hazards, and injury, and anything in the water’s path, including medical equipment, medications, homes, and vehicles, can be severely damaged or destroyed. Patients with cancer who are immunocompromised are a highly vulnerable post-flooding population and need special guidance.
Certain Cancers May Increase Risk of Type 2 Diabetes
Patients with lung, pancreatic, breast, brain, urinary tract, or uterine cancers may be more likely to develop new-onset type 2 diabetes after their cancer diagnosis, according to research findings published in Diabetes Care, and those who went on to develop type 2 diabetes experienced poorer overall health outcomes.
Nurse Scientists Are Leading Patient Care Discoveries in the Ever-Evolving World of Cancer Survivorship
The cancer survivorship program team at the University of Pennsylvania Abramson Cancer Center is conducting numerous research projects such as cancer treatment’s late effects, survivors’ quality of life and health behaviors, telemedicine for survivorship visits, and even an artificial intelligence–powered, mobile phone–based program to support patient adherence to guidance from survivorship visits.
Low Cost-Related Health Literacy May Prevent Survivors From Following Care Plans
Not understanding terms like deductible, copay, premium, coinsurance, and out-of-pocket maximum prevents many Americans from selecting a health insurance plan that meets their financial needs. Fewer than 40% of patients enrolled in high-deductible healthcare plans engage in effective financial behaviors, such as comparing prices or discussing costs with clinicians. High costs are a barrier for many patients and survivors to access high-quality cancer and survivorship care.
Oncology Nurse Educates the Public on the Evolution of Cancer Care and Survivorship
With care shifting to outpatient delivery and the increased availability of evidence-based support services, cancer care and survivor support has greatly evolved during the past 25 years, according to ONS member Carlin Callaway, DNP, MS, RN, ACNP-BC, ACNS-BC, AOCNP®, assistant professor and lead medical oncology advanced practice provider at the University of Colorado Cancer Center and member of the ONS Metro Denver Chapter, in a June 2022 public-facing blog post for the American Society of Clinical Oncology’s Cancer.Net website.
Data Coordinators and Oncology Nurses Collaborate to Create Accurate, Comprehensive Survivorship Care Plans
Coordinating survivorship care plans is an integral part of cancer care. When the Froedtert and Medical College of Wisconsin Cancer Network experienced challenges in implementing survivorship care plans, it created a brand-new medical role—survivorship data coordinator—to “initiate case findings for eligible patients, track patients completing treatment, notify physicians and advanced practice providers to populate the survivorship care plan, and schedule survivorship care plan appointments.”
Social and Community Context Matter in Cancer Care
A person’s zip code often matters more than their genetic code when it comes to their health. Where we live and work, how connected we are in our community, and how much support we have are core social determinants of health that also significantly affect cancer health outcomes.
Biden Adds New Members to Cancer Cabinet
With broad backgrounds in oncology genetics, immunology, and disparities, President Joe Biden’s three July 2022 appointments to the Cancer Cabinet will help guide the United States on opportunities to reduce cancer’s barriers and burden for underserved populations.
New Technology Tools Help Oncology APRNs Improve Patient Outcomes
Clinical decision support systems are tools integrated into electronic health records that include reminders for preventive care, evidence-based clinical practice guidelines, order sets, and alerts for drug prescribing. In health care, artificial intelligence converts data into knowledge to guide clinical decisions. When combined, the two technologies can guide advanced practice RNs and other providers with predictions and suggestions that go beyond human accuracy and specificity.
CMS Expands Access to High-Quality Care With Physician Payment Rule Proposal
To decrease cost and increase access to care, in July 2022 the Centers for Medicare and Medicaid Services proposed a conversion factor of $33.08 for the 2023 Physician Fee Schedule.
Nurses Are Pivotal to Advancing Biden’s Cancer Moonshot Initiative
As the most trusted professionals for 20 years in a row, nurses witness the needs of those in our care and are suited to translate them to legislatures, regulatory agencies, nongovernmental organizations, and insurers. We do that by speaking plainly about the impact that cancer has on patients and their families. As experts, our ideas and language can translate into practice changes to transform cancer care.
Promote Patient Self-Advocacy Across the Cancer Spectrum
Healthcare professionals are called to provide patient-centered care in an environment where they listen to patients’ goals and desires and support patient autonomy. However, heeding that call requires patients’ participation to voice their needs and concerns, and some patients may be reluctant to speak up for themselves.
Cost Can Prevent Patients From Receiving Follow-Up Care, Study Suggests
Financial considerations are notable barriers for patients with cancer receiving follow-up cancer care, according to study findings from the National Institutes of Health (NIH) All of Us Research Program.
Oncology Care Model Created New Opportunities for APRNs to Transform Cancer Care
Launched in 2016 as a pilot program from the Centers for Medicare and Medicaid Services Innovation Center to develop new payment and delivery system models, the Oncology Care Model had a lofty goal: drive improvements in providing high-quality and cost-effective care.
CDC Reports More Than 1.7 Million New Cancer Cases in 2019
More than 1.7 million new invasive cancer cases were reported in the United States in 2019, according to the U.S. Cancer Statistics from the Centers for Disease Control and Prevention (CDC) updated in June 2022.
CNS Survivorship Needs More Research, Funding, and Training, Expert Panel Says
Access and reimbursement, patient and provider education, core competencies, and survivorship research funding remain critical barriers for primary central nervous system (CNS) cancer survivorship, a team of National Cancer Institute Comprehensive Oncology Network Evaluating Rare CNS Tumors experts reported in a workshop summary published in Neuro-Oncology Advances.
The Clinical Pharmacist’s Role in Symptom Assessments
Healthcare professionals involved in direct patient care, such as nurses, pharmacists, advanced practice providers, and physicians, learn methods of symptom assessment during education and training, but each profession uses a slightly different lens. The ability to consider polypharmacy and drug-drug interactions in patient assessment is one of the most important skills a clinical pharmacist uses in daily practice. Clinical pharmacists caring for patients with cancer must identify drug-related side effects, monitor and manage patients during chronic drug therapy, and educate patients and members of the interprofessional team, all in the context of the intricacies of antineoplastic therapy and adherence assessment.
Symptom assessment gives oncology nurses a consistent matrix to directly evaluate the significance that symptoms have on patients’ distress, quality of life, and survival. Both symptoms and their impact can evolve throughout a patient’s cancer course, making high-quality and detail-oriented assessments an essential tool for successful treatment and management.
Community Health Centers Get Funding to Advance Equity in Cancer Screening and Follow-Up Care
With the relaunch of the Biden-Harris administration’s Cancer Moonshot initiative, the fight against cancer is back in the government spotlight. To support the Moonshot’s goals, in May 2022 the U.S. Department of Health and Human Services (HHS) allocated $5 million to the Health Resources and Services Administration-funded community health centers.
CMS’s Chronic Pain Experience Journey Map Will Help Patients and Providers
Highlighting the most prominent barriers that people accessing care face and the influencers acting on providers, the Centers for Medicare and Medicaid Services (CMS) unveiled in May Chronic Pain Experience Journey Map. The map came out of the work done under the 2019 Chronic Pain Stakeholder Engagement initiative to explore the serious role chronic pain has in patients’ lives.
Independent Advocates Help Patients With Dementia Navigate Cancer Care
Clinicians have an implicit—if not explicit—obligation to advocate for their patients. However, as health care’s complexity increases, independent advocates can help patients navigate systematic challenges throughout the continuum. Independent advocates follow the patient, not the reimbursement constraints, a chief distinction between us and clinical, facility, or agency case managers.
The Evolution of Ambulatory Care
Ambulatory oncology began to gradually evolve in the mid-2000s to include multiple aspects of the care continuum. Then suddenly, a pandemic skyrocketed that growth as institutions Raced to develop their ambulatory infrastructure to meet new and changing needs.
The Case of the Swift Sepsis Response
Simon is a 72-year-old patient diagnosed with myelodysplastic syndrome and acute myeloid leukemia. He underwent an HLA-identical sibling peripheral blood stem cell transplantation with fludarabine and melphalan as conditioning chemotherapies before the procedure. Simon is now more than 12 days posttransplant but still neutropenic with an absolute neutrophil count of 0. He has no signs of engraftment, is on total parenteral nutrition, and requires multiple blood transfusions and electrolytes through his central line catheter daily.
What Oncology Nurses Need to Know About Telehealth
Thrust into the mainstream in 2020, telehealth has transformed how patients with cancer receive some of their care, substituting certain traditional in-person office or clinic visits for phones, videos, and apps and devices that monitor patients’ health. It’s improved access to care in areas previously considered at risk for disparities: for example, patients in remote locations can be managed in an acute-care setting using television monitors, cameras, and call buttons to contact specialists.
Building a CAR T-Cell Program: How to Go From None to Done
Chimeric antigen receptor (CAR) T-cell therapy is a promising new treatment option for patients with certain types of cancer. As the field expands, institutions are exploring specialized service lines to provide the treatment, speakers said during a presentation on April 22, 2021, for the 46th Annual ONS Congress™ as they shared the lessons learned as their institutions established CAR T-cell therapy programs.
Involve the Entire Cancer Care Team to Effectively Implement Guidelines
Only 19% of strategies to implement clinical practice guidelines are fully effective and the majority (43%) are not effective at all, according to the findings from a clinical review in the European Union. Effective guideline implementation requires teamwork, interprofessional engagement, and selecting the most appropriate tool for the job.
Virtual Care for Patients With Cancer in New Jersey During COVID-19
The COVID-19 coronavirus pandemic is unchartered territory with many unknowns, especially a new reality that nurses may be experiencing for the first time: virtual patient care. Even at a distance, the team at Jefferson Health New Jersey Sidney Kimmel Cancer Center in Sewell wanted to ensure we offered the same level of care and encouragement to patients in all phases of the cancer continuum, so here’s what we found worked for us.
How Can Electronic Health Records Help Nurses Implement OCM Changes?
The Oncology Care Model (OCM) is a value-based payment system that the Centers for Medicare and Medicaid Services is piloting. OCM focuses on decreasing the cost of cancer care while continuing to provide high-quality care, including a high level of care coordination and navigation and adherence to national guidelines for care. Part of OCM requires implementing certain practice changes, including documenting a 13-point care plan for each patient.
Patient-Centered Care Through the Oncology Care Model
Better care. Smarter spending. Healthier people. Those are the three hallmark goals of the Oncology Care Model, a value-based payment system developed by the Centers for Medicare and Medicaid Service’s Center for Innovation.
How Is ONS Supporting OCM Nursing Practice?
The preliminary outcomes for performance in the first year of the Oncology Care Model (OCM) have shown modest but interesting results for the value-based payment model. Centers for Medicare and Medicaid Services’ year-one evaluation examined the initial impact of the new payment model on practice in terms of outcomes related to total cost of care per practice, unplanned hospital and emergency department visits, hospital visits, and patient-reported satisfaction with care for six-month episodes of chemotherapy for beneficiaries from July 1, 2016–June 30, 2017.
Senators Create Bipartisan Comprehensive Care Caucus
After years of confusion, discussion, debate, and dedicated advocacy work, lawmakers are finally understanding what palliative care is—symptom management, not hospice—and how it’s employed in care. The benefits of early palliative interventions for many diseases, including cancer, can improve quality of life for patients as they navigate their diagnoses. To increase awareness and availability of palliative care in practice, Senators Jacky Rosen (D-NV), John Barrasso, MD (R-WY), Deb Fischer (R-NE), and Tammy Baldwin (D-WI) launched the bipartisan Senate Comprehensive Care Caucus on July 31, 2019.
Bipartisan Reps Reintroduce Cancer Care Planning and Communications Act
In divisive times, fewer congressional bills find their way to the president’s desk without considerable bipartisan support. The dance of legislation is complex. Maneuvering through the legislative terrain and avoiding political landmines requires partnerships, expert data, and—at times—a little bit of luck. In the case of the Cancer Care Planning and Communications Act (H.R. 3835), that’s the story so far.
New Genetics Service Delivery Models Help Patients Access Genetic Counseling
As genetic and genomic testing become more common—and complex—in cancer diagnosis and treatment decisions, more efficient and accessible ways of providing comprehensive genetic care are needed. In their article in the February 2019 issue of the Clinical Journal of Oncology Nursing, Pierle and Mahon discussed the findings from their literature review, specifically pertaining to genetics care services across the cancer continuum, patient and system barriers to accessing care, new service delivery models, and oncology nurses’ role in providing comprehensive cancer genetics care services.
Oncology Urgent Care Clinics Are an Emerging Setting for Cancer Care Delivery
Patients with cancer are living longer, embarking on complex treatment regimens, and experiencing more complications associated with care. As a result, a large volume of patients with cancer require urgent or emergency visits throughout their disease trajectory. Although the need remains constant, what has evolved over time are the chief complaints that bring patients in, the care associated with complications, and new options to lower the burden and cost of care.
Caring for Patients Through All Levels of Survivorship
The medical terms for living with and beyond a cancer diagnosis identify patients as entering the survivorship phase of their cancer journey. However, as science continues to develop new treatments responsible for extending patients’ lives, new levels of survivorship are being determined.
Care Coordination Standardizes Monitoring for Patients Prescribed Oral Cancer Agents
Use of oral therapies requires healthcare teams to monitor patients for issues such as unreported side effects, medication nonadherence, and incorrect administration of medications. Although many patients do very well with this form of treatment, some patients, even with a significant amount of education before starting therapy, may have challenges.