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    Providing Expert Testimony in the Virginia State Senate
    Cancer healthcare advocacy
    Providing Expert Testimony in the Virginia State Senate
    March 14, 2019
    Summer Oncology Nursing Fellowship Program Supports Undergraduate Students
    Oncology nursing community
    Summer Oncology Nursing Fellowship Program Supports Undergraduate Students
    February 22, 2019
    Experience the Power of Patient-Centered Research Through PCORI
    Health Policy
    Experience the Power of Patient-Centered Research Through PCORI
    February 07, 2019
    Building Collaboration, Education With Oncology Nurses in Malawi
    Oncology nursing community
    Building Collaboration, Education With Oncology Nurses in Malawi
    January 30, 2019
    Reality-Based Leadership Helps Nurses Cut the Drama So They Can Problem Solve
    Nurse self-care
    Reality-Based Leadership Helps Nurses Cut the Drama So They Can Problem Solve
    December 18, 2018
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    Ancestry Analysis Identifies Genetic Cause for Increased Multiple Myelmoma in African Americans
    Research

    Ancestry Analysis Identifies Genetic Cause for Increased Multiple Myeloma in African Americans

    Three cytogenetic subtypes are particularly responsible for the increased incidence of multiple myeloma in people of African descent, according to the results of a study published in Blood Cancer Journal.

    March 20, 2019
    Adding Chemo to Immunotherapy May Resensitize Resistant Tumors
    Immunotherapy

    Adding Chemo to Immunotherapy May Resensitize Resistant Tumors

    Using chemotherapy with immune checkpoint inhibitors may reactivate tumors’ responses to immunotherapy, researchers concluded in a review article published in the Annals of Oncology.

    March 13, 2019
    Understand the Evidence for Exercise in Gynecologic Cancer-Related Fatigue
    Treatment side effects

    Understand the Evidence for Exercise in Gynecologic Cancer-Related Fatigue

    Cervical cancer is the fourth most common cancer in women and the seventh most common overall. Cancer-related fatigue (CRF) has an estimated prevalence of 50%–90% in all patients and has been reported to affect 17%–33% of women with gynecologic cancers for as long as three to eight years after diagnosis. Many national guidelines from organizations such as the American College of Sports Medicine, American Cancer Society, National Institute for Health and Care Excellence, and ONS all recommend exercise to improve fatigue in patients with cancer. But no research has synthesized the evidence for exercise as an intervention for fatigue specifically in patients with gynecologic cancers. 

    March 12, 2019
    Hospital-Acquired Conditions Reduced by Nearly 1 Million From 2014–2017
    Clinical practice

    Hospital-Acquired Conditions Reduced by Nearly 1 Million From 2014–2017

    According to an Agency for Healthcare Research and Quality (AHRQ) analysis, the number of hospital-acquired conditions (HACs) reported in the United States dropped by 910,000 (13%) from 2014–2017. 

    March 06, 2019
    Open Hysterectomy Has Better Outcomes Than Minimally Invasive Surgery in Cervical Cancer
    Research

    Open Hysterectomy Has Better Outcomes Than Minimally Invasive Surgery in Cervical Cancer

    Women with early-stage cervical cancer have higher recurrence rates and worse overall survival with minimally invasive radical hysterectomy than abdominal radical hysterectomy, according to the results of two studies published in the New England Journal of Medicine.  

    February 27, 2019
    Modifying Five Lifestyle Factors Could Change the U.S. Cancer Burden
    Cancer risk prevention

    Modifying Five Lifestyle Factors Could Change the U.S. Cancer Burden

    Tobacco, obesity, alcohol, diet, and physical activity are major risk factors for cancer, yet all are modifiable, according to findings released in a new report from the American Cancer Society. Reducing tobacco use is the highest priority, but interventions for all five risk factors are essential for a comprehensive U.S. cancer control plan.

    February 26, 2019
    CMS Proposes Medicare Coverage for CAR T-Cell Therapy
    Immunotherapy

    CMS Proposes Medicare Coverage for CAR T-Cell Therapy

    To improve access to new cancer therapies and provide national consistency in coverage, on February 15, 2019, the Centers for Medicare and Medicaid Services (CMS) announced a proposed plan of coverage with evidence development for CAR T-cell therapy. The public is invited to share comments for the next 30 days.

    February 21, 2019
    Shorter EBRT for Early Prostate Cancer Has Similar Outcomes
    Prostate cancer

    Shorter EBRT for Early Prostate Cancer Has Similar Outcomes

    Patients receiving hypofractionated external-beam radiation therapy (EBRT) for early-stage prostate cancer experienced similar outcomes and toxicities as those receiving standard radiation at lower doses over a longer period of time, the American Society for Radiation Oncology, American Society of Clinical Oncology, and American Urological Association say in a new clinical guideline.

    February 20, 2019
    Epigenetic Cervical Cancer Test May Be More Accurate Than Pap or HPV Tests
    Genetics & genomics

    Epigenetic Cervical Cancer Test May Be More Accurate Than Pap or HPV Tests

    An S5 methylation test detected 100% of grade 2 cervical intraepithelial neoplasms or worse, compared to a 50% detection rate for Pap or human papillomavirus (HPV) tests, according to the results of a recent study reported in the International Journal of Cancer.

    February 13, 2019
    Be Alert for Severe, Early-Onset Toxicities From 5-Fluorouracil and Capecitabine
    Clinical practice

    Be Alert for Severe, Early-Onset Toxicities From 5-Fluorouracil and Capecitabine

    Although 5-fluorouracil (5-FU) and capecitabine (the oral prodrug of 5-FU) are generally well tolerated, patients can experience severe toxicities from either drug that can be life-threatening if not treated quickly. Of the 275,000 patients who receive 5-FU each year, more than 1,300 die from 5-FU toxicity, or approximately 3–4 patients per day.

    February 12, 2019
    Survival Gains Make CAR T-Cell Therapy Cost-Effective for Pediatric Leukemia
    Immunotherapy

    Survival Gains Make CAR T-Cell Therapy Cost-Effective for Pediatric Leukemia

    When evaluated based on the cost per life-year gained, the chimeric antigen receptor (CAR) T-cell immunotherapy drug tisgenlecleucel is considered cost effective in pediatric B-cell acute lymphoblastic leukemia, researchers reported in a new study. The findings were published in JAMA Pediatrics.

    February 06, 2019
    What You Need to Know About Caring for Geriatric Patients With Cancer
    Patient quality of life

    What You Need to Know About Caring for Geriatric Patients With Cancer

    Cancer is largely a disease of an aged population. Estimates suggest that about 60% of all cancers are diagnosed in individuals aged 65 or older, and that number is expected to increase to 70% by 2030. Yet many nurses have little formal geriatric-specific training to care for this population’s unique needs.

    January 08, 2019
    New Edition of Palliative Care Guidelines Focus on Inclusivity, Responsibility
    Palliative care

    New Edition of Palliative Care Guidelines Focus on Inclusivity, Responsibility

    Palliative care is a necessary inclusion in the care of all people with a serious illness, no matter the diagnosis or setting, and it’s the responsibility all healthcare providers, including specialty providers in oncology.The National Consensus Project (NCP) expanded on these two key tenets in its new release of the fourth edition of the Clinical Practice Guidelines for Quality Palliative Care. ONS is one of 80 organizations endorsing the new guidelines.

    December 27, 2018
    Immunotherapy May Increase Risk for Hyperprogressive Lung Cancer
    Lung Cancer

    Immunotherapy May Increase Risk for Hyperprogressive Lung Cancer

    Some patients receiving checkpoint inhibitors for lung cancer may experience increased risk for hyperprogressive disease (HPD), according to results of a study reported in JAMA Oncology.

    December 26, 2018
    Lack of AR Expression May Cause Prostate Cancer Treatment Resistance
    Prostate cancer

    Lack of AR Expression May Cause Prostate Cancer Treatment Resistance

    Prostate cancer cells lacking androgen receptor (AR) expression do not respond to treatment and are more likely to grow, researchers reported in study findings published in Nature Communications. 

    December 24, 2018
    Patient Stress Linked to More Advanced Leukemia
    Research

    Patient Stress Linked to More Advanced Leukemia

    Patients with chronic lymphocytic leukemia (CLL) who experience more stress also have more cancer cells in their blood and elevated levels of three other advanced disease markers, according to results of a study published in Cancer. It is the first study to link stress with biologic disease markers in patients with CLL.

    December 19, 2018
    HPV 9-Valent Vaccine Approved for People Aged 27–45
    Cancer prevention

    HPV 9-Valent Vaccine Approved for People Aged 27–45

    In October 2018, the U.S. Food and Drug Administration expanded the approved use of the human papillomavirus (HPV) 9-valent vaccine to include women and men aged 27–45 years. Previously, the vaccine had been approved for males and females aged 9–26 years, but the expanded approval was granted after the application had undergone priority review.

    December 12, 2018
    Manage Afatinib’s Adverse Events to Keep Patients on Treatment
    Adverse events

    Manage Afatinib’s Adverse Events to Keep Patients on Treatment

    Ongoing therapy with afatinib—an oral, irreversible ErbB family blocker—for as long as it is effective and tolerable is considered first-line treatment for metastatic non-small cell lung cancer in patients with EGFR mutations. In their article in the October 2018 issue of the Clinical Journal of Oncology Nursing, Edwards, Adan, Lalla, Lacouture, O’Brien, and Sequist discussed the most common adverse events (AEs) associated with afatinib and their real-life experiences managing them in clinical practice to keep patients on therapy.

    December 11, 2018
    ONS Past President Sandra Lee Schafer, RN, MN, AOCN®
    ONS News

    ONS Past President Sandra Schafer Leaves a Legacy of Compassionate Leadership

    From her patients to her colleagues to the entire cancer care community, ONS Past President Sandra Lee Schafer, RN, MN, AOCN®, made everyone she touched feel special, inspiring and motivating a generation of oncology nurses in advancing care for patients with cancer. Schafer passed away on December 7, 2018, but her legacy of compassion and care lives on.

    December 10, 2018
    U.S. Spending on Antineoplastics Nearly Doubles From 2011–2016
    Treatments

    U.S. Spending on Antineoplastics Nearly Doubles From 2011–2016

    Dollars spent on cancer drugs increased from $26.8 billion in 2011 to $42.1 billion in 2016, according to the results of a study reported in the Journal of Oncology Practice.

    December 05, 2018
    Researchers Win Nobel Prize for Work in Cancer Immunotherapy
    Cancer research

    Researchers Win Nobel Prize for Work in Cancer Immunotherapy

    Two researchers whose discoveries led to the development of the first cancer immunotherapy treatments, immune checkpoint inhibitors, were awarded the 2018 Nobel Prize in Medicine in October.

    November 28, 2018
    WHO Cautions About Inactivity Pandemic and Disease Risk
    Research

    WHO Cautions About Inactivity Pandemic and Disease Risk

    No improvement in worldwide exercise levels has been seen since 2001, and, in fact, inactivity has worsened, data in a new report from the World Health Organization (WHO) indicated. The findings were published in Lancet Global Health.

    November 20, 2018
    Recent NSAID Use May Improve Ovarian Cancer Survival
    Research

    Recent NSAID Use May Improve Ovarian Cancer Survival

    Researchers have found that use of nonsteroidal anti-inflammatory drugs (NSAIDs) after diagnosis appears to improve survival for patients with epithelial ovarian cancer. The study results were published in Lancet Oncology.

    November 14, 2018
    An Oncology Nursing Overview of Biosimilars
    Clinical practice

    An Oncology Nursing Overview of Biosimilars

    Since the first biosimilar agent was approved by the U.S. Food and Drug Administration (FDA) in 2015, patients and providers have had concerns about the implications for their care and practice, respectively. Because 6 of the 12 biosimilar drugs currently approved in the United States have indications for oncology practice, oncology nurses have a responsibility to understand the drugs’ safety and efficacy for the patients in their care.

    November 13, 2018
    Tailored Psychotherapy Combats Depression in Advanced Cancer
    Psychosocial issues

    Tailored Psychotherapy Combats Depression in Advanced Cancer

    Just three to six sessions of a tailored psychotherapy program called CALM, or Managing Cancer and Living Meaningfully, reduced symptoms of depression or prevented the onset of depression in patients with recently diagnosed advanced cancer, according to findings from a study published in the Journal of Clinical Oncology.

    November 07, 2018
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    Elisa Becze BA, ELS, Editor
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