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    Cancer Rehabilitation Serves a Critical Role in Patient Care
    Prehabilitation
    Cancer Rehabilitation Serves a Critical Role in Patient Care
    October 11, 2019
    Complexity Is the Cornerstone of BMT Nursing
    Oncology nursing roles
    Complexity Is the Cornerstone of BMT Nursing
    October 07, 2019
    What the Research Says About Drug Interactions and Medical Cannabis
    Oncology drug research
    What the Research Says About Drug Interactions and Medical Cannabis
    October 04, 2019
    Take These Healthy Steps to Come Back From an Unexpected Event
    Nurse self-care
    Take These Healthy Steps to Come Back From an Unexpected Event
    September 27, 2019
    Uplift Young Adult Patients by Sharing YA Resources
    Patient Support
    Uplift Young Adult Patients by Sharing Resources
    September 20, 2019
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    Colorectal Cancer Diagnoses Increasing in Patients Younger Than 50
    Clinical practice

    Colorectal Cancer Diagnoses Increasing in Patients Younger Than 50

    Healthcare providers are seeing increasing numbers of younger patients with colorectal cancer, and they’re being diagnosed with more advanced stages of the disease, researchers reported in study findings published in the journal Cancer.

    October 16, 2019
    irAEs Linked to Improved Benefit From Pembrolizumab
    Immunotherapy

    irAEs Linked to Improved Benefit From Pembrolizumab

    Patients with advanced melanoma who received adjuvant therapy with pembrolizumab and subsequently developed immune-related adverse events (irAEs) saw a 63% reduced risk of recurrence, compared to 44% for those who did not develop irAEs. The study findings were presented at the 2019 American Society of Clinical Oncology annual meeting.

    October 09, 2019
    Patient Education Is Critical to Managing irAEs for Immune Checkpoint Inhibitors
    Immunotherapy

    Patient Education Is Critical to Managing irAEs for Immune Checkpoint Inhibitors

    By rebalancing the immune system and re-engaging mechanisms that tumor cells have shut off, immunotherapies such as immune checkpoint inhibitors enable patients’ own bodies to fight their cancers for them. But those same mechanisms can also result in immune-related adverse events (irAEs).

    October 08, 2019
    Pediatric Cancer Survivors Have Higher Mortality After Adult Breast Cancer Diagnosis
    Survivorship

    Pediatric Cancer Survivors Have Higher Mortality After Adult Breast Cancer Diagnosis

    Women who survived pediatric cancer but developed breast cancer as an adult are more than twice as likely to die prematurely, mostly from comorbid conditions, according to results of a study published in the Journal of Clinical Oncology.

    October 02, 2019
    Model May Help Predict Lung Cancer Risk in Patients With Nodules
    Cancer risk factors

    Model May Help Predict Lung Cancer Risk in Patients With Nodules

    A risk-prediction model that combines patients’ health history with clinical characteristics of their lung nodules may help physicians determine which will develop into cancer, according to the results of a study published in Cancer Prevention Research.

    September 25, 2019
    Vaccine May Boost CAR T-Cell Activity in Solid Tumors
    Research

    Vaccine May Boost CAR T-Cell Activity in Solid Tumors

    Researchers are testing a new approach using an amphiphilic cancer vaccine to deliver CAR T-cell therapy to solid tumors, and the results of preclinical studies are promising, according to findings published in the journal Science.

    September 18, 2019
    FDA Warns of Rare Lung Inflammation With Certain CDK 4/6 Inhibitors
    U.S. Food and Drug Administration (FDA)

    FDA Warns of Rare Lung Inflammation With Certain CDK 4/6 Inhibitors

    Palbociclib (Ibrance), ribociclib (Kisqali), and abemaciclib (Verzenio) used to treat some patients with advanced breast cancers may cause rare but severe inflammation of the lungs, the U.S. Food and Drug Administration (FDA) announced on September 13, 2019. It approved new warnings about the risk on the prescribing information and package insert for the entire class of cyclin-dependent kinase 4/6 (CDK 4/6) inhibitor medicines. However, “the overall benefit of CDK 4/6 inhibitors is still greater than the risks when used as prescribed,” the agency noted.

    September 13, 2019
    Hematologic Cancers Have Higher Long-Term Risk of Clots and Bleeding
    Research

    Hematologic Cancers Have Higher Long-Term Risk of Clots and Bleeding

    Patients with hematologic cancers have a 19% increased risk for blood clots or bleeding events even 10 years after diagnosis, according to the results of a study published in the Journal of Thrombosis and Haemostasis.

    September 11, 2019
    Company Recalls TPN Bags Because of Leak and Infection Risk
    Safety

    Company Recalls TPN Bags Because of Leak and Infection Risk

    Bags used to store and administer total parenteral nutrition (TPN) are being recalled because of leaks near the divider rod and channel when the rod is removed, the Metrix Company of Dubuque, IA, announced on September 9, 2019.

    September 10, 2019
    Why Aren’t Nurses Adhering to PPE Requirements?
    Safety

    Why Aren’t Nurses Adhering to PPE Requirements?

    Oncology nurses are dedicated to providing the best, safest cancer care to their patients—protecting them from medical harm and prolonging life. But when it comes to protecting themselves, nurses sometimes take shortcuts in wearing personal protective equipment (PPE) that guards them against exposure to hazardous drugs. 

    September 10, 2019
    Oncology Formulations Not Affected by Bevacizumab Recall
    Prescription medication

    Oncology Formulations Not Affected by Bevacizumab Recall

    On September 3, 2019, AmEx Pharmacy issued a voluntary recall of two dosages of injectable bevacizumab. Although injectable bevacizumab is used in cancer treatment, the formulations affected by the recall are for much smaller dosages that are used to treat eye diseases (i.e., macular degeneration and diabetic retinopathy).

    September 06, 2019
    Melanoma Death Rates Are Falling Fast, Thanks to Immunotherapy
    Immunotherapy

    Melanoma Death Rates Are Falling Fast, Thanks to Immunotherapy

    Two-year survival rates for patients with advanced melanoma increased quickly after the introduction of ipilimumab in 2011, according to an analysis published the journal Cancer.

    September 04, 2019
    Hyperthyroidism Treatment Linked to Increased Cancer Death Risk
    Cancer risk factors

    Hyperthyroidism Treatment Linked to Increased Cancer Death Risk

    Radioactive iodine treatment for hyperthyroidism is associated with long-term risk of death from solid cancers, particularly breast cancer, according to the results of a study published in JAMA Internal Medicine. 
     

    August 21, 2019
    CAR T Cells Show Promise in Solid Tumors
    Research

    CAR T Cells Show Promise in Solid Tumors

    Two recent studies demonstrated CAR T-cell therapy activity in certain types of solid tumors, according to results presented at the American Society of Clinical Oncology annual meeting. The CAR T cells used new targets outside of the CD19 targets used for the therapy’s current approvals in leukemia and lymphoma. 
     

    August 14, 2019
    Immunotherapy Experts Identify Key Oncology Nursing Priorities at ONS Summit
    Immunotherapy

    Immunotherapy Experts Identify Key Oncology Nursing Priorities at ONS Summit

    Care coordination, appropriate adverse event assessment and treatment, and rapid, continuous learning are essential priorities for oncology nurses to care for patients receiving immunotherapy, according to the experts who participated in ONS’s immunotherapy summit in March 2018. 

    August 13, 2019
    Clinical Trial Participants Average 6.5 Years Younger Than Actual Cancer Populations
    Research

    Clinical Trial Participants Average 6.5 Years Younger Than Actual Cancer Populations

    For the four most common cancer sites (breast, prostate, colorectal, and lung cancer), the median age of patients in clinical trials is an average of 6.5 years younger than the median age of patients diagnosed with that cancer. And the age disparity is worsening, researchers reported in JAMA Oncology. 

    August 07, 2019
    Incidence of Aggressive Uterine Cancer Is Increasing
    Research

    Incidence of Aggressive Uterine Cancer Is Increasing

    U.S. incidence rates for aggressive uterine cancer subtypes are quickly rising for women aged 30-70, especially among non-Hispanic black women, according to results of a study published in the Journal of Clinical Oncology.

    July 24, 2019
    High Fitness Linked to Lower Risk and Mortality in Lung and Colorectal Cancers
    Research

    High Fitness Linked to Lower Risk and Mortality in Lung and Colorectal Cancers

    Adults with the highest cardiorespiratory fitness levels have a reduced risk for lung and colorectal cancer—and a lower risk of death if they do develop the cancers, according to findings from a study published in Cancer.

    July 17, 2019
    Magnet Status Benefits Physicians, Too
    Research

    Magnet Status Benefits Physicians, Too

    Achieving Magnet recognition is the gold standard of a nursing program, demonstrating that an organization’s nursing leaders have established nursing excellence to improve outcomes for patients. And now the results of a new study published in Harvard Business Review show that excellent nurses are positively linked to physicians’ performance as well.

    July 10, 2019
    Collaboration Is Key to CAR T-Cell Therapy Management Across Settings
    Immunotherapy

    Collaboration Is Key to CAR T-Cell Therapy Management Across Settings

    As of February 2019, only 160 institutions across the United States are certified to administer CAR T-cell therapy, meaning many eligible patients may need to be referred to a treatment center outside of the local ambulatory or community cancer center where they had previously received treatment. The transition from primary oncologist to certified center and back again requires careful coordination to ensure important steps and information aren’t lost.

    July 09, 2019
    The Work We Do Now Affects Healthcare’s Future
    Nurse empowerment

    The Work We Do Now Affects Health Care’s Future

    The World Health Organization designated 2020 internationally as the Year of the Nurse and Midwife in honor of Florence Nightingale’s 200th birthday. To celebrate the work that nurses do globally, nursing organizations around the world are creating programs that offer recognition—as well as education, training, and professional development.

    July 08, 2019
    Test Predicts Which Women Will Benefit From Chemo for Breast Cancer
    Breast cancer

    Test Predicts Which Women Will Benefit From Chemo for Breast Cancer

    A prediction test accurately identifies which women with estrogen receptor (ER)-positive, HER2-negative breast cancer will benefit from adjuvant chemotherapy, according to the results of a study published in Breast Cancer Research and Treatment. 
     

    July 03, 2019
    Access to Care and Nondiscrimination Are Two Key Ways to Address Cancer Disparities, According to ONS and ANA Position Statements
    Cancer health disparities

    Access to Care and Nondiscrimination Are Two Key Ways to Address Cancer Disparities, According to ONS and ANA Position Statements

    Cancer knows no race, color, nationality, or ethnicity. But although any person may one day develop cancer, incidence and mortality rates for some cancers are disproportionately higher in certain racial, ethnic, geographic, or socioeconomic groups. Here are just a few of the many identified cancer disparities, according to the National Cancer Institute.

    June 27, 2019
    New CAR T-Cell Targets Show Safe Results in Early Clinical Trials
    Research

    New CAR T-Cell Targets Show Safe Results in Early Clinical Trials

    Findings from two phase I clinical trials presented at the American Association for Cancer Research 2019 annual meeting indicate that targeting CAR T cells against mesothelin for advanced solid tumors and HER2 for advanced sarcoma is safe and shows clinical antitumor activity.

    June 26, 2019
    Early Studies Show Cancer Vaccines Are Promising for Lynch Syndrome, Cervical Lesions
    Research

    Early Studies Show Cancer Vaccines Are Promising for Lynch Syndrome, Cervical Lesions

    Findings from two recent studies underscore that cancer vaccines may be a larger part of the next wave of novel cancer therapies. According to data presented at the American Association for Cancer Research 2019 annual meeting, vaccination with as few as four tumor antigens generated antigen-specific responses, reduced intestinal tumors, and improved survival in a mouse model of Lynch syndrome. 

    June 19, 2019
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    Elisa Becze BA, ELS, Editor
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