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    supportive oncology services
    Cancer screening
    Local Organizations Can Make a Big Difference in Cancer Care
    June 28, 2017
    Jackie Davenport
    Oncology nurse pride
    How Have Your Family Experiences With Cancer Impacted Your Decision to Become an Oncology Nurse?
    June 09, 2017
    Melanoma Awareness
    Melanoma
    Encourage Malignant Melanoma Awareness in May
    May 12, 2017
    Equality
    Ethics in nursing
    Are All Patients Treated Equally?
    May 05, 2017
    Double Helix
    Genetics & genomics
    The Story of Henrietta Lacks Sheds Light on Ethical Considerations in Genetic Testing
    April 28, 2017
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    Prostate Cancer Risk
    Cancer research

    Less Sleep May Increase Risk of Death From Prostate Cancer

    Men younger than 65 years who sleep less than six hours per night have an increased risk of death from prostate cancer, according to the results of a study presented at the American Association for Cancer Research 2017 annual meeting.

    June 28, 2017
    Combination therapies
    Melanoma

    Combination Treatment Improves Survival for Advanced Melanoma

    A combination of nivolumab and ipilimumab improved overall survival when compared to either drug alone, according to results from a recent study reported at the American Association for Cancer Research 2017 annual meeting.

    June 21, 2017
    BRCA Testing
    Genetics & genomics

    More Women Undergo BRCA Testing, but Not High-Risk Patients

    BRCA gene testing is on the rise for women who do not meet the referral requirements based on family history, researchers reported in study findings published in the American Journal of Preventive Medicine. At the same time, many high-risk women do not obtain the test and remain unidentified.

    June 14, 2017
    Substance Abuse and Addiction
    Pain management

    Managing Pain in Patients With Substance Use Disorder

    In their article in the April 2017 issue of the Clinical Journal of Oncology Nursing, Compton and Chang provided a guide for nurses caring for patients with substance use disorder (SUD), including overview, diagnosis, and treatment of SUD as well as its implications for pain management and cancer treatment considerations when a patient with SUD is diagnosed with cancer.

    June 13, 2017
    DNA Copying Causes Most Cancer Mutations
    Cancer research

    Random DNA Copying Causes Most Cancer Mutations

    Researchers at Johns Hopkins Kimmel Cancer Center have demonstrated that random, unpredictable DNA copying mistakes account for nearly two-thirds of the mutations that cause cancer. The results were reported in Science.

    June 07, 2017
    CAR T-Cell Immunotherapy
    Cancer research

    Gene-Editing Tool May Better Deliver CAR T-Cell Immunotherapy

    In mouse experiments, researchers have found that immune T cells that have been genetically engineered to express chimeric antigen receptors (CARs) using a new tool called CRISPR were more effective than CAR T cells that were engineered with conventional methods. The findings were reported in Nature.

    May 24, 2017
    Seborrheic Keratosis
    Melanoma

    Dermascopic Clues Help Identify Seborrheic Keratosis-Like Melanoma

    Melanomas that resemble seborrheic keratosis (SK) can be challenging to diagnose correctly. SKs are often removed without being evaluated dermascopically or sent for pathologic analysis, risking the possibility of missing a diagnosis of SK-like melanoma. A new study published in JAMA Dermatology outlined the key dermascopic clues that clinicians can use to identify SK-like melanomas to prevent treatment delays and achieve the best patient outcomes.

    May 18, 2017
    Cancer Clinical Trials
    Oncology clinical trials

    How One Institution Improved Accrual to Cancer Clinical Trials

    One of the key factors to a cancer clinical trial’s success is the ability to enroll an adequate number of patients in an appropriate timeframe. Identifying barriers to slow accrual and ways to address them can help researchers and nurse scientists make big steps in the fight against cancer in the era of the National Cancer Moonshot Initiative.

    May 17, 2017
    Melanoma Survivors
    Melanoma

    10% of Melanoma Survivors Report Intentional Tanning

    A study published in Cancer Epidemiology, Biomarkers, and Prevention looking at the ultraviolet radiation exposure and sun protection behaviors among melanoma survivors found that many survivors have room for improvement.

    May 10, 2017
    CAR T-Cell Therapy
    Immunotherapy

    Nursing Considerations for Adverse Events From CAR T-Cell Therapy

    Chimeric antigen receptor (CAR) T-cell therapy offers options for pediatric patients with relapsed or refractory acute lymphoblastic leukemia, but it comes with a unique set of side effects that can range from mild to severe. As the primary patient providers, oncology nurses are often the first to identify signs and symptoms of adverse events and acute changes in patients’ status. Understanding what to watch for can improve outcomes and help nurses deliver safe, effective care.

    May 09, 2017
    Lung Cancer Screening
    Lung Cancer

    High-Risk Lung Cancer Screening Rates Remain Low

    Despite U.S. Preventive Services Task Force (USPSTF) recommendations, screening rates for smokers at high risk for lung cancer remain very low, according to the findings from a new study published in JAMA Oncology.
     

    May 02, 2017
    Early-Stage Melanoma
    Melanoma

    Disease Symptoms Most Likely to Predict Recurrence of Early-Stage Melanoma

    Patients and healthcare providers are most likely to detect recurrence of early-stage melanoma based on symptom reports rather than routine imaging tests, according to the results of a study published in the Journal of the American College of Surgeons.

    April 26, 2017
    Patient in Bed
    Breast cancer

    Patients Treated for Early-Stage Breast Cancer Report Severe Side Effects

    Nearly half of patients treated for early-stage breast cancer report at least one severe side effect, according to the results of a study published in Cancer.

    April 19, 2017
    Nurses talking
    Clinical practice

    AJCC Cancer Staging System Will See Changes in 2018

    Beginning in January 2018, oncology nurses will see changes to the way their patients’ cancers are staged with the American Joint Committee on Cancer (AJCC) system. According to a presentation at the National Comprehensive Cancer Network annual conference in March 2017, when the AJCC 8th Edition Cancer Staging System takes effect on January 1, 2018, more cases may be classified as stage I, especially for patients with breast cancer.

    April 12, 2017
    Bortezomib May Improve Outcomes in Multiple Myeloma
    Multiple myeloma

    Bortezomib May Improve Outcomes in Multiple Myeloma

    Adding bortezomib to combination therapy with lenalidomide and dexamethasone may improve progression-free and overall survival in patients with newly diagnosed multiple myeloma. The study findings were published in Lancet.

    April 12, 2017
    cancer research finds significant increase in survival rates
    Research

    Annual Cancer Report Identifies Significant Increases in Survival

    As part of its Annual Report to the Nation on the Status of Cancer for 1975-2014, a group of organizations and agencies identified significant increases in cancer survival in the United States, with survival rates more than doubling for eight cancers.

    April 11, 2017
    Immunotherapy Agents
    Immunotherapy

    What Oncology Nurses Need to Know About Immunotherapy Agents

    As immunotherapeutic options for cancer treatments continue to grow, oncology nurses need a deeper understanding of the therapies, how they work, and how to manage their side effects, so they can continue to provide the best patient care.

    April 11, 2017
    Colorectal Cancer Rates in Younger Adults
    Cancer research

    Study Finds Increased Colorectal Cancer Rates in Younger Adults

    Although overall rates of colorectal cancer have been falling since the 1970s and ‘80s, incidence of the disease has been increasing dramatically in patients younger than 50 years, according to the results of a new study published in the Journal of the National Cancer Institute.

    April 05, 2017
    Antidepressant May Relieve Joint Pain From Aromatase Inhibitors
    Symptom management

    Antidepressant May Relieve Joint Pain From Aromatase Inhibitors

    The antidepression drug duloxetine, which is approved to treat depression, anxiety, fibromyalgia, and diabetes nerve pain, may also relieve treatment-induced joint pain in breast cancer survivors receiving aromatase inhibitor therapy, according to the results of a study presented at the San Antonio Breast Cancer Symposium.

    March 21, 2017
    Results from a new clinical trial have shown that the targeted therapy drug ibrutinib, a BTK inhibitor, can effectively treat graft-versus-host disease (GVHD), a common complication from allogeneic stem cell transplants. The study findings were reported at the American Society of Hematology’s 2016 annual meeting.
    Cancer research

    Ibrutinib May Improve GVHD Symptoms

    Results from a new clinical trial have shown that the targeted therapy drug ibrutinib, a BTK inhibitor, can effectively treat graft-versus-host disease (GVHD), a common complication from allogeneic stem cell transplants. The study findings were reported at the American Society of Hematology’s 2016 annual meeting.

    March 15, 2017
    calipers measuring fat
    Cancer risk factors

    Increasing Adult BMI May Raise Risk of Fatal Prostate Cancer

    Men whose body mass index (BMI) increases to obesity during adulthood may have a higher risk of fatal prostate cancer, according to the results of a study published in the Journal of the National Cancer Institute.

    January 29, 2017
    Research

    CD36 Protein and Dietary Fat May Combine to Increase Cancer Metastasis

    New research published in Nature may have identified one way cancer cells metastasize to spread and resist treatment. The study showed how a cancer protein interacts with dietary fat to facilitate metastasis and may pave the way for new cancer therapies.

    January 29, 2017
    Nurse navigator helping patient
    Research

    The Evolving Role of Oncology Nurse Navigators

    Care coordination is an integral component of every oncology nurse’s job, but the specific role of oncology nurse navigator (ONN) was developed to help address certain barriers to care, including difficulty navigating the healthcare system, poor communication, and lack of resources.

    January 28, 2017
    Cancer biology

    Cancer Cells May Use Neutrophil Traps to Metastasize

    Previous research has linked neutrophils to cancer metastasis, but a new study published in Science Translational Medicine may have uncovered more information about why this happens.
    The study’s researchers found that neutrophil extracellular traps (NETs), which the immune system normally uses to kill harmful pathogens, may help metastatic cancer cells form new tumors in other parts of the body.

    January 26, 2017
    nurse reviewing genetic results
    Cervical cancer

    New Genetic Test May Predict High-Risk Cervical Cancer

    A new genetic test that analyzes multiple sources of DNA may be able to detect high-risk cervical cancer more accurately than other available tests: it showed 90.9% sensitivity in identifying cervical intraepithelial neoplasia 2 lesions. The findings from the proof-of-concept study were reported in Cancer Prevention Research.

    January 24, 2017
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    Elisa Becze BA, ELS, Editor
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