More and more patients are turning to generative artificial intelligence (AI) tools such as ChatGPT and other chatbots to help them understand the complexity of their cancer diagnosis and associated genomic testing, an interprofessional team of genetics professionals and educators wrote in an article for the Clinical Journal of Oncology Nursing. However, they cautioned that the tools’ limitations could have “serious consequences” for patients.

Today’s technologies are tools that oncology nurses can use to transform cancer care—for their practice as well as their patients. Although the latest technologies are in a state of constant evolution, oncology nurses can take a leading role in guiding their application to and implementation in health care and cancer care.

Osimertinib (Tagrisso^®) received its first U.S. Food and Drug Administration approval for the treatment of metastatic non-small cell lung cancer in patients whose tumors have EGFR T790M variants in November 2015. Since then, the FDA has expanded its approval to other EGFR variants, including exon 19 deletions and exon 21 L858R variants. In the drug’s clinical trial, patients taking osimertinib alone experienced slower disease progression, with a median overall survival of 38.6 months.

Lisocabtagene maraleucel (Breyanzi^®) was first approved by the U.S. Food and Drug Administration (FDA) in 2021 for patients with relapsed or refractory large B-cell lymphoma (LBCL), high-grade B-cell lymphoma, primary mediastinal large B-cell lymphoma, and grade IIIB follicular lymphoma. In 2022, the FDA expanded its approval for the initial indication to include those with refractory disease or relapse within 12 months of first-line chemoimmunotherapy who are not eligible for hematopoietic stem cell transplantation.

Oxaliplatin (Eloxatin^®) is a platinum-based drug used since 2002 to treat colorectal cancer. It can cause serious hypersensitivity adverse reactions and has the unique side effect of reversible peripheral sensory neuropathy exacerbated by exposure to cold temperature or objects. It gets its name from its chemical structure, which has an oxalate ligand.