Changing Treatment Paradigms Embrace Longer Use of Systemic Breast Cancer Therapies

The abundance of clinical trials evaluating survival and treatment outcomes in women with breast cancer has resulted in a paradigm shift to more refined surgical treatment parameters and decreased the number of additional surgeries, according to researchers with Memorial Sloan-Kettering Cancer Center in New York, NY, but the ability of surgery to cure breast cancer remains unchanged. The researchers presented the results of their analyses on Wednesday, December 7, during the San Antonio Breast Cancer Symposium.

Accelerated Partial Breast Radiation Improves Quality of Life

Women treated with accelerated partial breast irradiation (APBI) reported a significantly better quality of life (QOL) compared to women treated with whole breast irradiation (WBI), a group of Italian researchers has found. They presented their results on Wednesday, December 7, at the San Antonio Breast Cancer Symposium.

Online Risk Assessment Tool Is Inconsistent Compared to Genomic Testing

A group of British researchers has found that with only minimal changes in clinical parameters because of a lack of perfect correlation between pathologists’ results, there is a significant difference in the 10-year predicted mortality on Adjuvant! Online, a breast cancer risk assessment tool.

ONS/ONCC Role Delineation Study Shows Oncology Nurse Navigators’ Role Continues to Evolve

Since ONS and the Oncology Nursing Certification Corporation conducted the first role delineation study in 2011, the oncology nurse navigator role has continued to change. Cancer care has evolved, and focus on care coordination has increased to improve quality and reduce costs.

Marybeth Singer

Providing Safe Quality Care for Patients Receiving Engineered, Non-Stem Cell Therapies

A number of non-stem cell therapies, including cellular vaccines and chimeric antigen receptor (CAR) T cells, are offered to cancer centers. “Demand is growing, with several CAR products heading for imminent U.S. Food and Drug Administration approval,” said Sarah Nikiforow, MD, PhD, Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School in Boston, MA.

10-Year TEAM Trial Results Confirm Optimal Breast Cancer Endocrine Therapy

The original Tamoxifen Exemestane Adjuvant Multinational (TEAM) study found no significant differences for disease free survival (DFS) and overall survival (OS) at five years between exemestane monotherapy and sequential treatment (tamoxifen followed by exemestane), but there is still no universal agreement on optimal endocrine therapy.

Oncology Nurses’ Role in Politics and Policy in the New Administration

The 2016 presidential race was one for the record books. This cycle saw two diametrically opposed candidates, in both style and ideology. They each represented a large segment of the American electorate and wanted to take the country in very different directions. But now it is over, and we can all go back to other endeavors. Right?

Why Does the FDA Place Clinical Holds on Investigational New Drug Clinical Trials?

You have a patient with cancer who is participating in a clinical trial. The patient has just been told that the trial has been placed on a clinical hold. What does that mean? What should you say to your patient?

CDC, FDA Say Younger Adolescents Need Only Two HPV Vaccine Doses

In October 2016, the Centers for Disease Control and Prevention (CDC) issued a recommendation that adolescents aged 9–14 need only two doses of the human papillomavirus vaccine at least six months apart, rather than the previously recommended three doses, to achieve immunity.