FDA Announces Oncology Center of Excellence
The U.S. Food and Drug Administration (FDA) recently announced, through the Office of Health and Constituent Affairs, that it has established the Oncology Center of Excellence (OCE). Longtime FDA official, Richard Pazdur, MD, has been named to lead the division as its first director. The OCE will make oncology “the first disease area to have a coordinated clinical review of drugs, biologics and devices across the agency’s three medical product centers,” according to the FDA.
Increasing Adult BMI May Raise Risk of Fatal Prostate Cancer
Men whose body mass index (BMI) increases to obesity during adulthood may have a higher risk of fatal prostate cancer, according to the results of a study published in the Journal of the National Cancer Institute.
CD36 Protein and Dietary Fat May Combine to Increase Cancer Metastasis
New research published in Nature may have identified one way cancer cells metastasize to spread and resist treatment. The study showed how a cancer protein interacts with dietary fat to facilitate metastasis and may pave the way for new cancer therapies.
Inherited Mutations Are More Common Than Thought in Early-Onset Colorectal Cancer
At least 16% of patients with early-onset colorectal cancer have at least one inherited gene mutation that increases their risk of cancer, and many of those mutations are undetected based on current screening guidelines, according to the results of a study published in JAMA Oncology.
The Evolving Role of Oncology Nurse Navigators
Care coordination is an integral component of every oncology nurse’s job, but the specific role of oncology nurse navigator (ONN) was developed to help address certain barriers to care, including difficulty navigating the healthcare system, poor communication, and lack of resources.
Cancer Cells May Use Neutrophil Traps to Metastasize
Previous research has linked neutrophils to cancer metastasis, but a new study published in Science Translational Medicine may have uncovered more information about why this happens.
The study’s researchers found that neutrophil extracellular traps (NETs), which the immune system normally uses to kill harmful pathogens, may help metastatic cancer cells form new tumors in other parts of the body.
New Genetic Test May Predict High-Risk Cervical Cancer
A new genetic test that analyzes multiple sources of DNA may be able to detect high-risk cervical cancer more accurately than other available tests: it showed 90.9% sensitivity in identifying cervical intraepithelial neoplasia 2 lesions. The findings from the proof-of-concept study were reported in Cancer Prevention Research.
Palliative Care, Opioids, and Biomarkers Lead NIH's 2016 Research Year in Review
Mammography Cutoffs Should Be Based on Individual Health History
Researchers conducting the largest study to date on screening mammography outcomes have found no evidence to support stopping mammography screenings at a certain age. The findings were presented at the 2016 Radiological Society of North America annual meeting.
Statin Use May Improve Overall Survival From Multiple Myeloma
A new study has found that use of statin medications in patients with multiple myeloma was associated with a decreased risk of all-cause and cancer-specific mortality. The findings were published in the Journal of Clinical Oncology.
Combination Therapy Shows Promise for Chronic Myeloid Leukemia
According to the results of a new study published in Science Translational Medicine, a combination regimen consisting of a BCR-ABL tyrosine kinase inhibitor and a B-cell lymphoma 2 inhibitor may one day result in a cure for chronic myeloid leukemia.
Smoking Causes Higher Proportion of Cancer Deaths in Southern States
CDC Releases Study on Breast Cancer Rates by Age and Ethnicity
Inotuzumab Ozogamicin May Improve Survival in ALL
Maintenance Treatment May Prolong Progression-Free Survival in Ovarian Cancer
Surgery Prolongs Survival for Patients With NSCLC
Poliovirus May Be Key to Treating Glioblastoma
Pembrolizumab Associated With Long-Term Survival in Advanced Melanoma
Pretreatment Anemia Predicts Poor Survival From NSCLC
New Class of Drugs Shows Promise in Treatment-Resistant Prostate Cancer
Sorafenib Adverse Events May Be More Common in Thyroid Cancer
What Nurses Need to Know About Talimogene Laherparepvec for Advanced Melanoma
Prostate Radiotherapy May Increase Bladder Cancer Risk
Blinatumomab May Induce Remission in Patients With Relapsed or Refractory ALL
Radiation Plus Chemotherapy Improves Survival From Low-Grade Gliomas
Proteins Targeting Tumor Microenviroment May Block Metastatic Ovarian Cancer Growth
Study Links Bladder Cancer Subtype to Breast Cancer
Low-Dose Metformin May Reduce Risk of Colorectal Adenomas
New Treatment Approach May Be Effective for Aggressive Ovarian Cancer
Discarded Excess U.S. Cancer Drugs Cost $1.8 Billion per Year
Annual Report on the Status of Cancer Released
Imaging Tests Are Overused in Early-Stage Breast Cancer
Missing Radiation Therapy Sessions Increases Risk of Recurrence
National Cancer Moonshot Initiative Could Learn From Open-Source Data Ideas
More Research Is Needed for Adolescent and Young Adult Cancers
Periodontal Disease May Increase Breast Cancer Risk, Especially in Women Who Smoke
Psychological Morbidities Linked to Young Adult Survivors of Blood Cancers
Association Found Between Vitamin D Deficiency and Leukemia Risk
President Addresses Precision Medicine at White House Summit
“You can match a blood transfusion to a blood type...what if matching a cancer cure to our genetic code was just as easy, just as standard? What if figuring out the right dose of medicine was as simple as taking our temperature?”