Incidence of Aggressive Uterine Cancer Is Increasing

July 24, 2019 by Elisa Becze BA, ELS, Editor

U.S. incidence rates for aggressive uterine cancer subtypes are quickly rising for women aged 30–70, especially among non-Hispanic black women, according to results of a study published in the Journal of Clinical Oncology (

Among all women, overall uterine cancer rates increased by about 1% per year from 2003–2015. But when looking at the two subtypes (endometrioid and the more aggressive nonendometrioid), incidence rates increased by 2.9% per year for all women. For non-Hispanic black women, the rates were even more dramatic: 25.9 per 100,000, compared to 11.4 for Caucasians, 10.1 for Hispanics, and 7.5 for Asian/Pacific Islanders. Additionally, the five-year relative survival rate was lower among all women with the nonendometriod subtype and black women had the lowest survival rates at any stage of diagnosis or subtype.

The authors said that more research is needed because nonendometriod is a rarer subtype and less is known about the disease. They called for investigations into its etiology to improve risk prediction and early detection, as well as research into the racial differences and disparities.

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