Treatment side effects
Know How to Properly Treat Immunotherapy Side Effects
Oncology nurses are intimately familiar with side effects related to chemotherapy. Advice for managing chemotherapy symptoms such as fatigue, diarrhea, dyspnea, skin toxicities, and increased risk of infection can be found in ONS’s Putting Evidence Into Practice (PEP) resources. However, immunotherapy treatments often offer similar side effects that are treated very differently from those associated with traditional treatments.
October 19, 2016
Sorafenib Adverse Events May Be More Common in Thyroid Cancer
Researchers have found that patients receiving sorafenib for differential thyroid cancer are more likely to experience adverse events from the drug, compared to patients with renal or hepatocellular cancers. The findings were published in JAMA Oncology.
July 19, 2016
Prostate Radiotherapy May Increase Bladder Cancer Risk
Patients with prostate cancer who undergo radiation treatment, especially brachytherapy, may be at increased risk of bladder cancer more than 10 years later, according to the results of a new study presented at the American Urological Association annual meeting.
July 12, 2016
Checkpoint Inhibitors May Cause Pseudoprogression and Dose-Limiting Side Effects
Immunotherapy agents, such as checkpoint inhibitors, are gaining popularity and press in cancer care. The agents block pathways used to slow immune activity, taking the brakes off the immune system so killer T cells stay in action and increase cancer cell death. Side effects often mimic autoimmune activity as the immune system stays in overdrive.
July 05, 2016
Manage Common Ocular Toxicities From Tyrosine Kinase Inhibitors
Alopecia, rash, peripheral neuropathy: it’s a well-known fact that systemic cancer therapies often damage healthy tissues while fighting cancer cells. However, ocular toxicity from newer molecularly targeted cancer agents such as tyrosine kinase inhibitors (TKIs) is generally underestimated and under-reported.
June 07, 2016
Oncology health literacy
Patient Education Needs With Pazopanib Therapy for Soft Tissue Sarcoma
Few therapies are effective for treating advanced soft tissue sarcoma, so pazopanib quickly became a commonly prescribed therapy once it was approved for STS in April 2012. Although pazopanib is safe and effective, patients must be educated about its administration and side effects.
March 08, 2016
Why Your Patients Need to Get Up, Get Moving
What’s one of the most common symptoms reported by patients with cancer? Fatigue. Regardless of diagnosis, it seems that nurses are constantly looking for ways to help their patients fight against the symptoms brought on by their disease and its treatment.
January 21, 2016
How to Manage the Side Effects of New Targeted Agents for Metastatic Colorectal Cancer
Although about 50% of patients can be cured after surgical resection when colorectal cancer (CRC) is detected early, the remaining patients aren’t as fortunate. CRC that metastasizes before detection or recurs following surgery remains a major treatment challenge.
January 12, 2016
Outpatient Oncology Drug Series: Doxorubicin Is the Infamous Red Devil
Doxorubicin is a cytotoxic chemotherapy drug and an antitumor antibiotic in the anthracycline group. You’ll see this drug quite a lot In the outpatient setting, and most commonly, you’ll use it to treat patients with breast cancer.
April 10, 2015
Crush Constipation With This Old-Time Recipe
Constipation is no fun for anyone, but for patients with cancer this all-too-common side effect is especially troublesome. Oncology nurses need to know how to advise patients when they bring up this somewhat uncomfortable subject.
March 17, 2015
Outpatient Oncology Drug Series: Confidently Administer 5-Fluorouracil
5-Fluorouracil, or most commonly referred to as simply 5-FU, is a cytotoxic chemotherapy drug that is classified as an antimetabolite and, within that class, belongs to the pyrimidine analogue family.
February 23, 2015
When Should Appetite Stimulants Be Discussed With Patients With Unintended Weight Loss From Cancer Treatment?
Unintended weight loss and anorexia in patients with cancer is associated with decreased performance status, reduced response and tolerance to treatment, decreased survival, and reduced quality of life.
January 20, 2015
Outpatient Oncology Drug Series: Oxaliplatin Hates the Cold
Oxaliplatin is a cytotoxic (toxic to normal cells) chemotherapy drug that is classified as an alkylating agent as well as a platinum analogue. It is indicated for a number of different cancers including colorectal, esophageal, gastric, hepatobiliary, Non-Hodgkin lymphoma, ovarian, pancreatic, and testicular cancer.
January 16, 2015
Outpatient Oncology Drug Series: Paclitaxel Packs a Punch
Oncology nursing is a field in which you are challenged on a regular basis to expand your knowledge because of the constantly changing field of treatments being used. Whether you are new or seasoned, it can be difficult to stay on top of the numerous agents used for varying diagnoses.
December 12, 2014
Yoga May Help Survivors Manage Side Effects of Lung Cancer
Lung cancer symptoms and side effects often persist in patients as they transition to the survivorship period, resulting in increased stress, poorer functional status, lower quality of life, and higher mortality. However, emerging evidence suggests that yoga can help patients with cancer and other chronic illnesses manage symptoms.
February 11, 2014
The Case of the Pyrogenic Platelet Product
Jackie is administering six units of pooled random donor platelets to Stuart, a patient with myelodysplastic syndrome. The transfusion was started at 120 ml per hour, per hospital policy. When Jackie rechecked Stuart’s vital signs at 15 minutes, she noted that his temperature had increased from 37.1°C to 38.1°C. In addition, Stuart was chilling. What would you do?
December 17, 2013
The Case of the Severe Sudden-Onset Swelling
Gina is filling in for the triage nurse at her facility’s outpatient solid tumor department. She receives a call from a patient who reports severe swelling in her left arm after returning from a trip on the opposite side of the United States. She says the skin in her arm and hand is quite tight, and that her hand was throbbing when she woke up this morning. What would you do?
October 15, 2013
The Case of the Suspicious Sunburn
William calls your office complaining of painful redness and blisters on his chest. He admits that during the recent warm weather, he hadn’t been wearing a shirt while working in the yard. He initially thought it was a sunburn, but the symptoms continued to worsen and were unrelieved by typical sunburn remedies. Upon reviewing William’s chart, you see that he recently received radiation and chemotherapy therapy for Hodgkin disease. What would you do?
June 18, 2013
Oncology drug research
FDA Approves Lenalidomide for Mantle Cell Lymphoma
On June 5, 2013, the U.S. Food and Drug Administration approved lenalidomide capsules (Revlimid®, Celgene Corporation), for the treatment of patients with mantle cell lymphoma whose disease has relapsed or progressed after two prior therapies, one of which included bortezomib.
June 06, 2013
The Case of the Compacted Colon
Bob, a 61-year-old man with multiple myeloma, calls his hematologist’s office complaining of worsening constipation despite increasing his fiber and liquid intake. Yesterday, he stopped taking his ondansetron because he remembered that it can cause constipation, but now he’s nauseated in addition to being constipated. What would you do?
May 07, 2013